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Murine Cervical Aortic Transplantation Model using a Modified Non-Suture Cuff Technique
 

Murine Cervical Aortic Transplantation Model using a Modified Non-Suture Cuff Technique

Article DOI: 10.3791/59983-v • 10:11 min • November 2nd, 2019
November 2nd, 2019 •
1, 1, 1, 1, 2, 1, 1, 1, 1, 1, 1, 1, 1, 1,3
1Department of General, Visceral, and Transplant Surgery, Ludwig Maximilian University of Munich, 2Walter-Brendel-Centre of Experimental Medicine, Ludwig Maximilian University of Munich, 3Department of General, Visceral and Cancer Surgery, University Hospital of Cologne, University of Cologne

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Here, we present a protocol of heterotopic aortic transplantation in mice using the non-suture cuff technique in a cervical murine model. This model can be used to study the underlying pathology of chronic allograft vasculopathy (CAV) and can help evaluate new therapeutic agents in order to prevent its formation.

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Keywords: Murine Cervical Aortic Transplantation Non-suture Cuff Technique Heterotopic Aortic Transplantation Common Carotid Artery Vascular Surgery Microsurgical Technique
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