Waiting
Processando Login

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / Analysis of Group IV Viral SSHHPS Using In Vitro…
JoVE Journal
Immunology and Infection

Este de .

JoVE Journal Immunology and Infection
Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
 

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

Article DOI: 10.3791/60421-v • 10:40 min • December 21st, 2019
December 21st, 2019 •
1, 2, 2
1National Center for Advancing Translational Sciences, National Institutes of Health, 2United States Naval Research Laboratory

Capítulos

Resumo
Automatic Translation

We present a general protocol for identifying short stretches of homologous host-pathogen protein sequences (SSHHPS) embedded in the viral polyprotein. SSHHPS are recognized by viral proteases and direct the targeted destruction of specific host proteins by several Group IV viruses.

Tags

Group IV Viral SSHHPS In Vitro Methods In Silico Methods Viral Protease Cleavage Sites Targeted Destruction Of Host Proteins Immune Responses Protease Assays Zika SSHHPS Sequences Brain And Eye Development Activity Of The Protease Protein BLAST Scissile Bond Viral Polyprotein Non-redundant Protein Sequences Host Genome PHI-BLAST Pattern Sequence BLAST Hits
Read Article
Waiting X
Simple Hit Counter