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JoVE Journal Neuroscience
3D Modeling of Dendritic Spines with Synaptic Plasticity
 

3D Modeling of Dendritic Spines with Synaptic Plasticity

Article DOI: 10.3791/60896-v • 07:13 min • May 18th, 2020
May 18th, 2020 •
*1, *1
1Center for Mathematics, Computation and Cognition, Federal University of ABC
* These authors contributed equally

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The protocol develops a three-dimensional (3D) model of a dendritic segment with dendritic spines for modeling synaptic plasticity. The constructed mesh can be used for computational modeling of AMPA receptor trafficking in the long-term synaptic plasticity using the software program Blender with CellBlender and MCell.

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Keywords: 3D Modeling Dendritic Spines Synaptic Plasticity Computational Modeling Mesh Generation Blender CellBlender Spine Head Spine Neck Cylinder Dendrite
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