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JoVE Journal Cancer Research
Profilering af følsomhed over for målrettede terapier i EGFR-mutant NSCLC-patientafledte organoider
 
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Profilering af følsomhed over for målrettede terapier i EGFR-mutant NSCLC-patientafledte organoider

Article DOI: 10.3791/63039-v • 08:52 min • November 22nd, 2021
November 22nd, 2021 •
1,2,3, 1,2, 1,2,3, 1,2,3
1Department of Medicine, University of California, San Francisco, 2Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 3Department of Cellular and Molecular Pharmacology, University of California, San Francisco

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Denne protokol beskriver en standardiseret evaluering af lægemiddelfølsomheder over for målrettede signalhæmmere i NSCLC-patientafledte organoidmodeller.

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Kræftforskning udgave 177 Organoid lungeorganoid BOB NSCLC lungekræft osimertinib EGFR målrettet hæmmer resistens
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