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Rapid Viscoelastic Characterization of Airway Mucus Using a Benchtop Rheometer
 

Rapid Viscoelastic Characterization of Airway Mucus Using a Benchtop Rheometer

Article DOI: 10.3791/63876-v • 08:47 min • April 21st, 2022
April 21st, 2022 •
1, 1, 1, 1, 2, 2, 1,3, 1,4
1Marsico Lung Institute / CF Center, The University of North Carolina at Chapel Hill, 2Rheonova, 3Department of Pulmonary and Critical Care Medicine, The University of North Carolina at Chapel Hill, 4Department of Pediatric, Pediatric Pulmonology Division, The University of North Carolina at Chapel Hill

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The viscoelastic properties of mucus play a critical role in mucociliary clearance. However, traditional mucus rheological techniques require complex and time-consuming approaches. This study provides a detailed protocol for the use of a benchtop rheometer that can rapidly and reliably perform viscoelastic measurements.

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Keywords: Mucus Rheology Viscoelastic Characterization Airway Mucus Benchtop Rheometer Muco-obstructive Diseases Biomarkers Sputum Sample Sample Handling Sample Preparation Mucus Viscosity
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