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Chapters
- 00:04Introduction
- 00:56Preparation of Nude Mouse Ear Skin Tissue
- 01:46Preparation of Human Skin Tissue
- 02:26Lipid Imaging and Application of Topical Formulation
- 03:11Experimental Setup for Drug Quantification and Data Analysis
- 08:53Results: Analysis of the Skin for Tissue Movement and Concentration of Drug at Different Timepoints
- 10:28Conclusion
En sammenhængende Raman scattering imaging metode til at visualisere og kvantificere farmaceutiske forbindelser i huden er beskrevet. Dette papir beskriver hudvævsforberedelse (human og mus) og topisk formuleringsapplikation, billedoptagelse for at kvantificere spatiotemporale koncentrationsprofiler og foreløbig farmakokinetisk analyse for at vurdere topisk lægemiddellevering.
