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原位Xenografting人类荧光素酶标记的恶性外周神经鞘瘤细胞
在体内
测试候选治疗药物
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
Orthotopic Xenografting of Human Luciferase-Tagged Malignant Peripheral Nerve Sheath Tumor Cells for
in vivo
Testing of Candidate Therapeutic Agents
Please note that all translations are automatically generated.
Click here for the English version.
原位Xenografting人类荧光素酶标记的恶性外周神经鞘瘤细胞
在体内
测试候选治疗药物
DOI:
10.3791/2558-v
•
07:10 min
•
March 07, 2011
•
Amy N. Turk
,
Stephanie J. Byer
,
Kurt R. Zinn
,
Steven L. Carroll
3
1
Department of Pathology
,
University of Alabama at Birmingham – UAB
,
2
Department of Radiology
,
University of Alabama at Birmingham – UAB
,
3
Department of Cell Biology and Neurobiology
,
University of Alabama at Birmingham – UAB
Chapters
00:05
Title
01:27
Preparation of Non-nude Immunodeficient Mice and MPNST Cell
02:14
Grafting Procedure
05:10
Bioluminescence as a Measure of Successful Tumor Grafting
06:52
Conclusion
Summary
Automatic Translation
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Automatic Translation
一种可靠荧光素酶标记的人类恶性外周神经鞘肿瘤细胞移植到免疫缺陷小鼠坐骨神经的方法是描述。利用生物发光成像显示肿瘤移植和动物为研究组随机分离的标准进行了适当的建立进行了讨论。
Tags
Orthotopic Xenografting
Human Malignant Peripheral Nerve Sheath Tumor Cells
In Vivo Testing
Candidate Therapeutic Agents
Animal Model
Preclinical Trials
Transgenic Mice
Xenograft Models
Immunodeficient Mice
Therapeutic Ranges
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