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在小鼠永久性大脑中动脉结扎术中的应用
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The Application Of Permanent Middle Cerebral Artery Ligation in the Mouse
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在小鼠永久性大脑中动脉结扎术中的应用

DOI:
10.3791/3039-v

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08:27 min

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July 25, 2011

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, ,
1Department of Pharmacology and Physiology,University of Rochester, 2Department of Neurology,University of Alabama at Birmingham, 3Departments of Anesthesiology, Pharmacology and Physiology,University of Rochester

Chapters

  • 00:05Title
  • 01:22Pre-surgical Preparation
  • 03:25Surgical Procedure and MCA Ligation
  • 05:29TTC Staining and Determination of Stroke Colume
  • 06:06Directions to use ImageJ Software
  • 07:26Representative Results
  • 08:07Conclusion

Summary

Automatic Translation

Automatic Translation

大脑中动脉（MCA）结扎是一种技术，研究在动物模型局灶性脑缺血。在此方法中，通过开颅暴露大脑中动脉和烧灼结扎。此方法提供了高度重复性的脑梗死体积和增加手术后的生存率率比现有的其他方法。

Tags

Permanent MCA LigationFocal Cerebral IschemiaStrokeAnimal ModelsPMCAoCraniotomyElectrocoagulationInfarctsCortical RegionsStriatal RegionsNeuroprotective CompoundsReproducible InfarctsPost-survival RatesMCA Artery

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