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Chapters
- 00:05Title
- 02:34Longitudinal Assessment of Bone Density Using the IVIS Lumina XR
- 04:47Image Analysis of IVIS X-ray Scans
- 07:37Representative Results: Bone Density Loss after SCI in the Tibia and Femur
- 10:08Conclusion
A longitudinal examination of bone loss in the femurs and tibiae of adult mice was performed following spinal cord injury using sequential low-dose X-ray scans. Tibia bone loss was detected throughout the study, while bone loss in the femur was not detected until 40 days post injury.
Tags
Longitudinal EvaluationMouseHind LimbBone LossSpinal Cord InjuryIn Vivo MethodologyOsteoporosisFracturesSensory FunctionBone Mineral DensityBone Mineral ContentMechanical DisuseNeuronal SignalingHormonal ChangesRodent ModelsGeneration Of New TherapiesNull And Transgenic MiceMinimally-invasiveReliableReproducibleQuantifiable MethodsDiagnosisTreatment MethodsPrevention Of SCI-induced Osteoporosis
