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Neuroscience

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Forebrain Electrophysiological Recording in Larval Zebrafish
 

Forebrain Electrophysiological Recording in Larval Zebrafish

Article DOI: 10.3791/50104-v 06:00 min January 24th, 2013
January 24th, 2013

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Summary

A simple method to record extracellular field potentials in the larval zebrafish forebrain is described. The method provides a robust in vivo read-out of seizure-like activity. This technique can be used with genetically modified zebrafish larvae carrying epilepsy-related genes or seizures evoked by administration of convulsant drugs.

Tags

Keywords: Forebrain Electrophysiology Larval Zebrafish Epilepsy Seizures Extracellular Recording Convulsant Drugs Genetic Manipulation Vertebrate Model In Vivo Screening Brain Activity
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