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Neuroscience

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Spinal Cord Transection in the Larval Zebrafish
 

Spinal Cord Transection in the Larval Zebrafish

Article DOI: 10.3791/51479-v 06:57 min May 21st, 2014
May 21st, 2014

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Summary

After spinal transection, adult zebrafish have functional recovery by six weeks post-injury. To take advantage of larval transparency and faster recovery, we present a method for transecting the larval spinal cord. After transection, we observe sensory recovery beginning at 2 days post-injury, and C-bend movement by 3 days post-injury.

Tags

Keywords: Spinal Cord Transection Larval Zebrafish Sensory Recovery Motor Recovery Axonal Regrowth Spinal Neurogenesis Regeneration C-bend Movement Free Swimming
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