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Chapters
- 00:05Title
- 01:26Synthesis of Biotin-Fc-cysteine
- 04:46Characterization of Biotin-Fc-cysteine and Immobilization on a Gold Surface
- 05:56Results: Synthesis and Immobilization of Biotin-Fc-cysteine on a Gold Surface
- 06:32Conclusion
The synthesis of asymmetric species of ferrocene is challenging using solution techniques. This report focuses on the methods carried out to produce a ferrocene-biotin bioconjugate using facile and clean reactions accomplished via solid-phase synthesis. Incorporation of a thiolate moiety is shown to impart the ability for immobilization on gold surfaces.
