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Demonstration of the Rat Ischemic Skin Wound Model
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Demonstration of the Rat Ischemic Skin Wound Model

Demonstration of the Rat Ischemic Skin Wound Model

DOI:
10.3791/52637-v

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08:35 min

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April 01, 2015

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, , , ,
1Department of Molecular Pharmacology and Physiology,University of South Florida, 2Department of Surgery,University of South Florida, 3Wound Recovery and Hyperbaric Medicine Center,Kent Memorial Hospital

Chapters

  • 00:05Title
  • 01:44Surgical Instrument and Operative Preparation
  • 03:09Creating Excisional Wounds and Bipedicled Flap
  • 05:16Post-operative Procedures, Wound Measurements and Dressing Changes
  • 06:55Results: Ischemic Wound Healing in Rats
  • 08:01Conclusion

Summary

Automatic Translation

Automatic Translation

The rat, due to its size, availability, and rather docile behavior, has been utilized as a research model for many years. The goal of this protocol is to utilize the rat as an ischemic skin wound healing model to provide valuable insight into the pathophysiology of chronic wounds.

Tags

Rat Ischemic Skin Wound ModelChronic WoundsImpaired Cardiovascular FunctionIschemic Skin FlapReduced VascularizationIncreased InflammationDelayed Wound ClosureSilicone SheetPanniculus Carnosus MuscleWound Healing Studies

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