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Miniosmotic植入泵和交货道示踪研究在病理情况下脑重组
JoVE Journal
Neuroscience
This content is Free Access.
JoVE Journal Neuroscience
Implantation of Miniosmotic Pumps and Delivery of Tract Tracers to Study Brain Reorganization in Pathophysiological Conditions
DOI:

10:32 min

January 18, 2016

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Chapters

  • 00:05Title
  • 01:11Preparation of Miniosmotic Pumps
  • 02:25Implantation of Miniosmotic Pumps
  • 05:03Removal of the Miniosmotic Pump
  • 05:57Pressure Tract Tracer Injection at 45o Angles on the Right Motor Cortex
  • 08:26Results: Recovery of Infarcted Brain After Delivery of Recombinant Human Erythropoietin
  • 09:40Conclusion

Summary

Automatic Translation

In order to study brain reorganization under pathological conditions we used miniosmotic pumps for direct protein delivery into the brain circumventing the blood brain barrier. Tract tracers are then injected to study alterations in brain connectivity under the influence of the protein.

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