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Chapters
- 00:05Title
- 00:40Gastrointestinal Tract Harvest
- 02:03Permeability Measurement
- 04:13Results: Representative Intestinal Permeability Investigations
- 05:09Conclusion
This protocol describes the use of excised intestinal tissue preparations or "intestinal sacs" as an ex vivo model of intestinal barrier function. This model may be used to assess integrity of both the epithelial barrier and the mucous gel layer at specific intestinal sites in animal models of digestive disease.
