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Construção de Engineered Definido cardíaca humana Tecidos para estudar os mecanismos da terapia celular cardíaca
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy
DOI:

11:51 min

March 01, 2016

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Chapters

  • 00:05Title
  • 00:58Cell Culture and Sorting of Differentiated Cardiomyocytes
  • 04:50Collection of Reaggregated Cardiac Cells
  • 06:32Generation of Human Engineered Cardiac Tissues
  • 09:45Results: Contractile Force Measurement Using Human Engineered Cardiac Tissues
  • 11:05Conclusion

Summary

Automatic Translation

This manuscript describes the creation of defined engineered cardiac tissues using surface marker expression and cell sorting. The defined tissues can then be used in a multi-tissue bioreactor to investigate mechanisms of cardiac cell therapy in order to provide a functional, yet controlled, model system of the human heart.

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