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Bioengineering

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JoVE Journal Bioengineering
Selective Cell Elimination from Mixed 3D Culture Using a Near Infrared Photoimmunotherapy Technique
 

Selective Cell Elimination from Mixed 3D Culture Using a Near Infrared Photoimmunotherapy Technique

Article DOI: 10.3791/53633-v • 05:18 min • March 14th, 2016
March 14th, 2016 •
1, 1, 1
1Molecular Imaging Program, National Cancer Institute

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Summary
Automatic Translation

Eliminating specific cells without damaging other cells is extremely difficult, especially in established tissue, yet there is an urgent need for a cell elimination method in the tissue engineering field. Here, we present a method for specific cell elimination from a mixed 3D cell culture using near infrared photoimmunotherapy (NIR-PIT).

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Keywords: 3D Cell Culture Near Infrared Photoimmunotherapy Selective Cell Elimination IR700 Conjugation Monoclonal Antibody Spheroid Tissue Engineering Regenerative Medicine
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