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Immunology and Infection

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JoVE Journal Immunology and Infection
Intra-tracheal Administration of Haemophilus influenzae in Mouse Models to Study Airway Inflammation
 

Intra-tracheal Administration of Haemophilus influenzae in Mouse Models to Study Airway Inflammation

Article DOI: 10.3791/53964-v • 09:56 min • March 2nd, 2016
March 2nd, 2016 •
1, 1, 1
1Baylor Institute for Immunology Research, Baylor Research Institute

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Summary
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We demonstrate the procedure for intra-tracheal inoculation of Haemophilus influenzae into the lower respiratory tracts of mice. This is a very useful tool to study signaling pathways that regulate airway inflammation in mouse models.

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Keywords: Intra-tracheal Administration Haemophilus Influenzae Mouse Model Airway Inflammation Lung Inflammation Immune Response NTHi Bacterial Infection Trachea Intubation Lung Euthanasia
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