Journal
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De cellules souches Basé Immunité Engineered contre l'infection à VIH dans le modèle humanisé Souris
JoVE Journal
Medicine
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JoVE Journal Medicine
Stem-cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model
DOI:

11:38 min

July 02, 2016

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Chapters

  • 00:05Title
  • 01:07Construction of Humanized Mice Engineered with CD4 Chimeric Antigen Receptor: Thymus Processing
  • 02:18Liver Processing
  • 05:18Tissue Transplantation to Construct Genetically Engineered Mice
  • 09:28Results: Characteristics of CD4 Chimeric Antigen Receptor Modified Cells
  • 10:39Conclusion

Summary

Automatic Translation

This protocol describes the methods in constructing a humanized bone-marrow/liver/thymus mouse model with stem cell-based engineered immunity against HIV infection.

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