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연속 IV 주입은 뇌졸중 유발 뇌 부종을 연구하는 마우스에 아르기닌 - 바소프레신​​ 수용체 차단 코니 밥탄의 선택 처리 경로입니다
JoVE Journal
Medicine
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JoVE Journal Medicine
Continuous IV Infusion is the Choice Treatment Route for Arginine-vasopressin Receptor Blocker Conivaptan in Mice to Study Stroke-evoked Brain Edema
DOI:

08:44 min

September 01, 2016

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Chapters

  • 00:05Title
  • 00:48In Vivo Stroke Induction
  • 03:06Neurological Deficit Scoring (NDS) and Filament Removal
  • 04:14Intravenous Catheter Jugular Vein Installation for Continuous 48 Hr Treatment
  • 06:28Results: Representative Effects of Continuous I.V. or I.P. Conivaptan Treatment on Stroke-evoked Brain Edema
  • 07:18Conclusion

Summary

Automatic Translation

Our studies have revealed that the beneficial effects of conivaptan are dependent on the method of delivery after experimental stroke in mice. We have developed a research protocol for delivery of the receptor blocker via IV catheter on stroke-evoked brain edema formation in mice.

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