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制备和表征亲脂阿霉素前药胶束

JoVE Journal
Bioengineering

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JoVE Journal Bioengineering

Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles

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制备和表征亲脂阿霉素前药胶束

DOI:

10.3791/54338-v

•

09:56 min

•

August 02, 2016

•

Feng Li, Candace Snow-Davis, Chengan Du, Mikhail L. Bondarev, Marilyn D. Saulsbury, Simone O. Heyliger

¹School of Pharmacy,Hampton University

Chapters

00:05Title
01:00Synthesis of DOX-PA
03:10Preparation of DOX-PA Micelles by Film-dispersion Method
04:23Characterization of DOX-PA Micelles
07:02Results: Characterization of DOX-PA and Micelles Formulations
09:08Conclusion

Summary

Automatic Translation

一个亲脂性的阿霉素前体药物的制备和表征协议加载1,2- distearoyl- SN -glycero -3- phosphoethanolamine- N - [氨基（聚乙二醇）-2000]（DSPE-PEG）胶束描述。

Tags

Keywords: Lipophilic Doxorubicin Pro-drug Micell Formulations Drug Loading Drug Stability Drug Targeting Nanomedicine DOX-PA DSPE-PEG Silica Gel Column Thin Layer Chromatography Dulbecco’s Phosphate Buffer

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