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小鼠加速动脉硬化的诱导："电线损伤"模型
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
Induction of Accelerated Atherosclerosis in Mice: The “Wire-Injury” Model
Please note that all translations are automatically generated.
Click here for the English version.
小鼠加速动脉硬化的诱导："电线损伤"模型
DOI:
10.3791/54571-v
•
00:05 min
•
August 25, 2020
•
Adelina Curaj
,
Wu Zhoujun
,
Mareike Staudt
,
Elisa A. Liehn
2
1
Institute for Molecular Cardiovascular Research
,
RWTH Aachen University
,
2
Human Genetic Laboratory
,
University of Medicine and Pharmacy
Chapters
00:04
Title
00:38
Hyperlipidemia Inducement and Wire Injury
03:53
Results: Representative Restenosis Plaque Analysis
05:02
Conclusion
Summary
Automatic Translation
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Automatic Translation
本研究描述了小鼠加速动脉硬化诱导的侵入性程序。与其他使用电或低温诱发损伤的方法相比，机械诱导损伤模仿再血管化治疗后人类的再病状况，是研究有关分子机制的理想之选。
Tags
Keywords: Wire-injury Model
Accelerated Atherosclerosis
Mouse Model
Carotid Artery
Endothelial Denudation
Hyperlipidemia
Atherogenic Diet
Revascularization
Restenosis
Molecular Mechanisms
Injury Response
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