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Fabrikation af ekstracellulære matrix-afledte Skum og Mikrobærere som Tissue-specifikke cellekultur og Delivery Platforms
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1Biomedical Engineering Graduate Program,The University of Western Ontario, 2Department of Anatomy & Cell Biology, Schulich School of Medicine & Dentistry,The University of Western Ontario, 3Department of Chemical Engineering,Queen’s University, 4Department of Chemical & Biochemical Engineering, Faculty of Engineering,The University of Western Ontario
Chapters
- 00:05Title
- 00:52Decellularized Tissue Processing
- 01:41Extracellular Matrix (ECM) Suspension Preparation
- 04:01ECM-derived Foam Fabrication
- 04:58ECM-derived Microcarrier Fabrication via Electrospraying
- 07:11Preparation of Foams and Microcarriers for Cell Culture
- 08:55Results: Fabricated ECM-derived Foams and Microcarriers
- 10:36Conclusion
Den vævsspecifikke ekstracellulær matrix (ECM) er en vigtig mediator af cellefunktion. Denne artikel beskriver fremgangsmåder til syntetisering af rene ECM-afledte skum og mikrobærere, som er stabile i kultur uden behov for kemisk tværbinding til applikationer i avanceret 3D in vitro cellekulturmodeller eller som pro-regenererende bioscaffolds.
