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Fluorescentie gebaseerde neuraminidase remmingstest om de gevoeligheid van de influenza virussen zijn voorgesteld om de neuraminidase remmer Class of Antivirals
JoVE Journal
Immunology and Infection
This content is Free Access.
JoVE Journal Immunology and Infection
Fluorescence-based Neuraminidase Inhibition Assay to Assess the Susceptibility of Influenza Viruses to The Neuraminidase Inhibitor Class of Antivirals
DOI:

09:31 min

April 15, 2017

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Chapters

  • 00:05Title
  • 01:00Determining the Neuraminidase Activity of Viruses
  • 02:29Assessing Virus Seceptibility to NA Inhibitors Using the NA Inhibition Assay
  • 05:18Calculation of IC50 Values
  • 07:01Results: Susceptibility of Influenza Viruses to the Neuraminidase Inhibitor Class of Antivirals
  • 08:55Conclusion

Summary

Automatic Translation

We beschrijven het gebruik van een fenotypische fluorescentie-gebaseerde neuraminidase remming test om de gevoeligheid van influenza A en B virussen beoordelen in de neuraminidase-remmer klasse van antivirale middelen.

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