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Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles
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Developmental Biology
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JoVE Journal Developmental Biology
Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles

Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles

DOI:
10.3791/55837-v

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05:50 min

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June 13, 2017

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, , ,
1Department of Rehabilitation Sciences,University of Kentucky, 2Department of Physiology,University of Kentucky

Chapters

  • 00:05Title
  • 01:10Osmotic Pump Implantation
  • 02:49Direct Neurotrophin 4 (NTF4) Injection and Visualization
  • 04:42Results: Representative Effects of NTF4 Administration on Rat Laryngeal Muscle Fiber Size, Innervation, and Neuromuscular Junction Formation
  • 05:09Conclusion

Summary

Automatic Translation

Automatic Translation

Here, we present a protocol to describe the use of neurotrophin 4 (NTF4) systemically and directly to remodel rat aging laryngeal muscles.

Tags

Keywords: SubcutaneousNeurotrophin 4Osmotic PumpsMuscular InjectionAgingLaryngeal MusclesVocal FunctionMuscle RemodelingMuscle AtrophyOtolaryngologySurgical ProcedureAseptic TechniqueAnesthesiaRat Model

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