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三维组织工程化排列的星形胶质细胞网络, 以概括发展机制和促进神经系统再生
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
DOI:

08:52 min

January 10, 2018

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Chapters

  • 00:05Title
  • 01:03Agarose Hydrogel Micro-Column Fabrication
  • 03:51ECM Core Fabrication
  • 05:26Seeding Micro-columns with Astrocytes
  • 06:32Results: Formation of Astrocyte Bundles within Hydrogel Micro-columns over Time
  • 07:54Conclusion

Summary

Automatic Translation

我们展示了自组装的发展, 三维束纵向排列星胞和过程内的新型生物材料装箱。这些被设计的 "活脚手架", 显示微米尺度的直径, 但长度延长厘米, 可作为试验床研究神经发育机制或促进 neuroregeneration 通过引导神经元迁移和/或轴突寻.

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