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Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
DOI:

14:52 min

January 13, 2018

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Chapters

  • 00:00Title
  • 00:49Equipment setup and configuration (45 minutes)
  • 01:47Participant Greeting and Preparation (10 minutes)
  • 02:23EEG and Additional Recordings Preparation (10 minutes)
  • 03:53Steps to Minimise Movement and Baseline Recordings (15 minutes)
  • 04:25Preparation for Anesthetic Administration (15 minutes)
  • 05:21Stepwise Gas Level Administration (120 minutes)
  • 07:07End of Procedure and Debrief (45 minutes)
  • 07:44Representative Results
  • 13:11Conclusion

Summary

Automatic Translation

Simultaneous magnetoencephalography and electroencephalography provides a useful tool to search for common and distinct macro-scale mechanisms of reductions in consciousness induced by different anesthetics. This paper illustrates the empirical methods underlying the recording of such data from healthy humans during N-Methyl-D-Aspartate-(NMDA)-receptor-antagonist-based anesthesia during inhalation of nitrous oxide and xenon.

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