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Chemistry
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酶联反应合成 l-赖氨酸手性氨基醇的研究
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Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Please note that all translations are automatically generated.
Click here for the English version.
酶联反应合成 l-赖氨酸手性氨基醇的研究
DOI:
10.3791/56926-v
•
09:14 min
•
February 16, 2018
•
Aurélie Fossey-Jouenne
,
Carine Vergne-Vaxelaire
,
Anne Zaparucha
1
Génomique Métabolique, Genoscope, Institut François Jacob
,
CEA, CNRS, Univ Evry, Univ Paris-Saclay
Chapters
00:04
Title
00:48
Semi-preparative One-pot Biocatalytic Reaction, Reaction Monitoring, and Product Analysis
03:17
Semi-preparative One-pot Biocatalytic Reaction: Second and Third Steps
06:01
Results: Investigation of Pyridoxal Phosphate Dependent Decarboxylase (PLP DC) Activities towards Hydroxy Lysine Derivatives
07:56
Conclusion
Summary
Automatic Translation
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Automatic Translation
手性氨基醇是在有机合成中用作支架的多功能分子。从 l-赖氨酸开始, 用酶催化的酶联反应合成氨基醇, 然后将相应羟基氨基酸的羧酸基团 diastereoselective羧.
Tags
Enzymatic Cascade Reactions
Chiral Amino Alcohols
L-lysine
Chiral Auxiliaries
Pharmaceutical Therapy
One-pot Procedure
Deoxygenase KD-01
DNFB Derivatization
HPLC Analysis
Deoxygenase KD-02
Decarboxylase Dccpin
PLP
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