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Journal
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Immunology and Infection
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血管紧张素 II. 型小鼠白细胞滚动和粘附的可视化技术及缺陷
JoVE Journal
Immunology and Infection
This content is Free Access.
JoVE Journal
Immunology and Infection
Visualizing Leukocyte Rolling and Adhesion in Angiotensin II-Infused Mice: Techniques and Pitfalls
Please note that all translations are automatically generated.
Click here for the English version.
血管紧张素 II. 型小鼠白细胞滚动和粘附的可视化技术及缺陷
DOI:
10.3791/56948-v
•
10:16 min
•
January 04, 2018
•
Jeremy Lagrange
,
Sabine Kossmann
2
,
Klytaimnistra Kiouptsi
,
Philip Wenzel
2,3
1
Center for Thrombosis and Hemostasis Mainz
,
University Medical Center Mainz
,
2
Center for Cardiology
,
University Medical Center Mainz
,
3
German Center for Cardiovascular Research (DZHK)
Chapters
00:05
Title
00:51
Jugular Catheter Implantation and Carotids Preparation
05:11
Assessment of Rolling and Adhering Leukocytes/LysM+ Cells with Intravital Video Microscopy
07:29
Results: Leukycote Rolling and Adhesion in Angiotensin II-Infused Mice
09:18
Conclusion
Summary
Automatic Translation
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Automatic Translation
这份手稿描述了使用转基因的记者小鼠和不同的管理途径荧光染料在血管紧张素 II 诱导高血压使用活体视频显微镜的血管评价免疫细胞的活化作用及其能够滚动和坚持内皮。
Tags
Intravital Microscopy
Leukocyte Rolling
Leukocyte Adhesion
Angiotensin II
Hypertension
Vascular Dysfunction
Blood Cells
Vascular Endothelium
Jugular Vein
Surgical Procedure
Mouse Model
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