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脊髓损伤后压力溃疡的小鼠模型
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Bioengineering
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JoVE Journal Bioengineering
Mouse Model of Pressure Ulcers After Spinal Cord Injury
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脊髓损伤后压力溃疡的小鼠模型

DOI:
10.3791/58188-v

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06:51 min

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March 09, 2019

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, , , , ,
1Department of Biomedical Engineering,Rutgers University, 2Center for Engineering in Medicine,Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children, 3Department of Surgery,Yale School of Medicine, Yale University

Chapters

  • 00:04Title
  • 00:35T9-T10 Spinal Laminectomy
  • 02:22T9-T10 Complete Spinal Injury
  • 03:11Induction of Skin Pressure Ulcer after Complete SCI
  • 04:22Post-operative Animal Care, Euthanasia, and Tissue Collection for Histology
  • 05:07Results: Skin Wound Histology and Impact on Healing
  • 06:15Conclusion

Summary

Automatic Translation

Automatic Translation

在这里, 我们描述了一个简单的方法, 以诱导临床相关的皮肤压疮 (pu) 在小鼠模型的脊髓损伤 (sci)。该模型可用于临床前的研究, 筛选不同的治疗方法治疗 pu 在 sci 患者。

Tags

Mouse ModelPressure UlcersSpinal Cord InjuryWound HealingLaminectomySCI SurgeryTransectionAnalgesiaBetadineDepilatory Cream

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