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Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
DOI:

06:30 min

September 11, 2018

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Chapters

  • 00:04Title
  • 00:36Femoral Artery Cannulation for Map Arterial Pressure (MAP) Monitoring
  • 01:41Brain Access, Renal Sympathetic Nerve Isolation, and Recording Quality Assessment
  • 05:02Results: Representative RSNA and Blood Pressure Responses to IV Phenylephrine Injection
  • 05:30Conclusion

Summary

Automatic Translation

Methods for measuring sympathetic and cardiovascular responses to central nervous system (CNS) manipulations are important for advancing neuroscience. This protocol was developed to assist scientists with measuring and quantifying acute changes in renal sympathetic nerve activity (RSNA) in anesthetized rats (non-survival).

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