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JoVE Journal Engineering
Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies
 

Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies

Article DOI: 10.3791/61021-v • 08:33 min • April 12th, 2022
April 12th, 2022 •
1, 1, 1, 2, 2, 1, 2, 1, 1,3, 1
1PMI R&D, Philip Morris Products S.A., 2PMI R&D, Philip Morris Research Laboratories Pte. Ltd., 3Applied Mathematics, University of Twente

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Summary
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The protocol describes the settings and use of a capillary aerosol generator for continuous production of controlled aerosol from a multispecies liquid solution, suitable for steady large-volume aerosol delivery (e.g., in vivo inhalation studies).

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Keywords: Capillary Aerosol Generator CAG Aerosol Generation Inhalation Toxicology Electronic Cigarette Liquid Composition Temperature Control Air Flow Nucleation Condensation Protocol Assembly Heating Elements Thermocouple Push-in Fittings O-rings Peak Adapter Coupling Peristaltic Pump Compressed Air
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