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Neuroscience
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创伤性脑损伤的神经炎症和血流动力学反应的系统分析
JoVE Journal
Neuroscience
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JoVE Journal
Neuroscience
Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
Please note that all translations are automatically generated.
Click here for the English version.
创伤性脑损伤的神经炎症和血流动力学反应的系统分析
DOI:
10.3791/61504-v
•
07:21 min
•
May 27, 2022
•
Rowan O. Brothers*
1
,
Sara Bitarafan*
2,3
,
Alyssa F. Pybus
3
,
Levi B. Wood*
1,2,3
,
Erin M. Buckley*
1,4,5
1
Wallace H. Coulter Department of Biomedical Engineering
,
Georgia Institute of Technology and Emory University
,
2
George W. Woodruff School of Mechanical Engineering
,
Georgia Institute of Technology
,
3
Parker H. Petit Institute for Bioengineering and Bioscience
,
Georgia Institute of Technology
,
4
Department of Pediatrics
,
Emory University School of Medicine
,
5
Children’s Research Scholar
,
Children’s Healthcare of Atlanta
Chapters
00:05
Introduction
00:33
Mild Traumatic Brain Injury (TBI) Weight‐Drop Model
01:20
Diffuse Correlation Spectroscopy (DCS) Cerebral Blood Flow Assessment
01:54
Multiplexed Cytokine and Phospho‐Protein Quantification
05:16
Results: Representative Traumatic Brain Injury Neuroinflammatory and Hemodynamic Response Analyses
06:37
Conclusion
Summary
Automatic Translation
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Automatic Translation
该协议提出了表征神经炎症和血流动力学对轻度创伤性脑损伤的反应的方法,并将这些数据整合为使用偏最小二乘回归的多变量系统分析的一部分。
Tags
Neuroinflammatory
Hemodynamic
Traumatic Brain Injury
Partial Least Squares Regression
Multivariate System Analysis
Mouse Model
Diffuse Correlation Spectroscopy
Cytokine
Phospho-protein
BCA Assay
Multiplex Immunoassay
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