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Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril
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JoVE Journal Chemistry
Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

DOI:
10.3791/61682-v

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10:02 min

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October 03, 2020

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, , , , ,
1Department of Chemistry,University College London (UCL), 2Institute for Materials Discovery,University College London (UCL)

Chapters

  • 00:04Introduction
  • 01:05Synthesis of Gold Nanoparticles
  • 02:24Seeded Gold Nanoparticle Growth
  • 04:13CB7-Uric Acid Complex Formation
  • 06:08Uric Acid Surface-Enhanced Raman Spectroscopy Sensing
  • 07:19Results: Representative Gold Nanoparticle Characterization and Uric Acid Detection within Gold Nanoparticle: CB7 Nanoaggregates
  • 09:30Conclusion

Summary

Automatic Translation

Automatic Translation

A host-guest complex of cucurbit[7]uril and uric acid was formed in an aqueous solution before adding a small amount into Au NP solution for quantitative surface-enhanced Raman spectroscopy (SERS) sensing using a modular spectrometer.

Tags

SERSUric Acid DetectionGold NanoparticlesCucurbit[n]urilBiomarker QuantificationDiagnostic ApplicationsEnvironmental MonitoringAggregation KineticsGold Seed SynthesisSeeded Growth

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