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Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size (LEfSe) in Microbiome Data
JoVE Journal
Genetics
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JoVE Journal Genetics
Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size (LEfSe) in Microbiome Data
DOI:

04:57 min

May 16, 2022

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Chapters

  • 00:04Introduction
  • 00:39Linear Discriminant Analysis Effect Size (LEfSe) Native Analysis
  • 01:49LEfSe Online Analysis (Galaxy)
  • 03:05Results: Representative Microbiome LEfSe Characterization
  • 04:21Conclusion

Summary

Automatic Translation

LEfSe (LDA Effect Size) is a tool for high-dimensional biomarker mining to identify genomic features (such as genes, pathways, and taxonomies) that significantly characterize two or more groups in microbiome data.

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