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Måling af glukoseoptagelse i Drosophila-modeller af TDP-43 Proteinopati
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Measuring Glucose Uptake in Drosophila Models of TDP-43 Proteinopathy
DOI:

07:07 min

August 03, 2021

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Chapters

  • 00:04Introduction
  • 00:41Drosophila Ventral Nerve Cord Dissections
  • 01:43Image Acquisition
  • 03:27Image Processing, ROI Selection, and Data Analysis
  • 04:46Results: Glucose Uptake Measurement in Drosophila Models of TDP-43 Proteinopathy
  • 06:32Conclusion

Summary

Automatic Translation

Glukoseoptagelse øges i Drosophila motoriske neuroner, der er påvirket af TAR DNA-bindende protein (TDP-43) proteinopati, som angivet af en FRET-baseret, genetisk kodet glukosesensor.

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