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JoVE Journal
Neuroscience

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Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique
 

Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique

Article DOI: 10.3791/64538-v 07:17 min September 7th, 2022
September 7th, 2022

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Summary

Minimally invasive techniques and a simple laboratory device improve the reproducibility of the spinal cord injury model by reducing operative damage to the experimental animals and allowing anatomical morphology maintenance. The method is worthwhile because the reliable results and reproducible procedure facilitate investigations of the mechanisms of disease reparation.

Tags

Keywords: Mouse Contusion Spinal Cord Injury Minimally Invasive Technique Anatomical Structure Weight Drop Spinal Cord Locating Laminectomy Paraspinal Muscle Dissection Microenvironment Analysis
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