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在大鼠模型中通过结扎和脂多糖注射的组合 诱导 牙周炎
JoVE Journal
Immunology and Infection
Author Produced
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JoVE Journal Immunology and Infection
Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model
DOI:

06:14 min

February 17, 2023

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Chapters

  • 00:04Introduction
  • 00:55Animal Anesthesia and Procedure Preparation
  • 02:48Retentive Ligature Technique and Intragingival Pg‐LPS Injection
  • 03:42Post‐Procedure Follow‐Up
  • 04:47Results: Analysis of the Alveolar Bone and Maxillary Molars
  • 05:46Conclusion

Summary

Automatic Translation

在这项研究中,通过保留结扎和重复注射源自牙龈卟啉单胞菌的脂多糖的组合,在第上颌磨牙周围超过14天,提出了诱导牙周炎的大鼠模型。结扎和LPS注射技术可有效诱发牙周炎,导致牙槽骨质流失和炎症。

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