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Dynamisk lysspredningsanalyse til bestemmelse af partikelstørrelsen af jern-kulhydratkomplekser
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Dynamisk lysspredningsanalyse til bestemmelse af partikelstørrelsen af jern-kulhydratkomplekser

Article DOI: 10.3791/63820-v • 04:40 min • July 7th, 2023
July 7th, 2023 •
1, 2, 2, 1, 1, 1, 1
1Vifor Pharma Group, Vifor Pharma Management Ltd, 2Section of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva

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Dynamisk lysspredning (DLS) har vist sig som et egnet assay til evaluering af partikelstørrelsen og fordelingen af intravenøst administrerede jern-kulhydratkomplekser. Protokollerne mangler imidlertid standardisering og skal ændres for hvert jern-kulhydratkompleks, der analyseres. Denne protokol beskriver anvendelsen af og de særlige overvejelser ved analyse af jernsaccharose.

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Medicin nr. 197
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