Alex MacKenzie Children's Hospital of Eastern Ontario Research Institute Biography Publications Institution JoVE Articles Alex MacKenzie has not added a biography. If you are Alex MacKenzie and would like to personalize this page please email our Author Liaison for assistance. Publications Transcriptomic RNAseq Drug Screen in Cerebrocortical Cultures; Towards Novel Neurogenetic Disease Therapies Human Molecular Genetics. Jun, 2018 | Pubmed ID: 29901742 Inhibitor of Apoptosis Proteins, NAIP, CIAP1 and CIAP2 Expression During Macrophage Differentiation and M1/M2 Polarization PloS One. 2018 | Pubmed ID: 29518103 Establishing Core Outcome Sets for Phenylketonuria (PKU) and Medium-chain Acyl-CoA Dehydrogenase (MCAD) Deficiency in Children: Study Protocol for Systematic Reviews and Delphi Surveys Trials. Dec, 2017 | Pubmed ID: 29258568 Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency Genetics. Dec, 2017 | Pubmed ID: 29061647 Neuronal Apoptosis Inhibitory Protein (NAIP) Localizes to the Cytokinetic Machinery During Cell Division Scientific Reports. 01, 2017 | Pubmed ID: 28059125 DNM1L-related Mitochondrial Fission Defect Presenting As Refractory Epilepsy European Journal of Human Genetics : EJHG. 07, 2016 | Pubmed ID: 26604000 The Search for Pompe Patients in Canada: Assessing Feasibility of a National Disease Registry to Facilitate Research Journal of Neuromuscular Diseases. 2015 | Pubmed ID: 27858639 Human Growth Hormone Increases SMN Expression and Survival in Severe Spinal Muscular Atrophy Mouse Model Journal of Neuromuscular Diseases. 2014 | Pubmed ID: 27858661 VPAC2 Receptor Agonist BAY 55-9837 Increases SMN Protein Levels and Moderates Disease Phenotype in Severe Spinal Muscular Atrophy Mouse Models Orphanet Journal of Rare Diseases. 2014 | Pubmed ID: 24405637 Specific Combination of Compound Heterozygous Mutations in 17β-hydroxysteroid Dehydrogenase Type 4 (HSD17B4) Defines a New Subtype of D-bifunctional Protein Deficiency Orphanet Journal of Rare Diseases. Nov, 2012 | Pubmed ID: 23181892 A Generalizable Pre-clinical Research Approach for Orphan Disease Therapy Orphanet Journal of Rare Diseases. Jun, 2012 | Pubmed ID: 22704758 Prolactin Increases SMN Expression and Survival in a Mouse Model of Severe Spinal Muscular Atrophy Via the STAT5 Pathway The Journal of Clinical Investigation. Aug, 2011 | Pubmed ID: 21785216 Estrogen Suppresses Uterine Epithelial Apoptosis by Inducing Birc1 Expression Molecular Endocrinology (Baltimore, Md.). Jan, 2008 | Pubmed ID: 17901126 Distinct Expression of Neuronal Apoptosis Inhibitory Protein (NAIP) During Murine Development Neuroreport. Mar, 2002 | Pubmed ID: 11930148 The Neuronal Apoptosis Inhibitory Protein is a Direct Inhibitor of Caspases 3 and 7 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2002 | Pubmed ID: 11896143 CHRIMCY: A Proposed Institute for Research on Reproduction, Development, and Mother, Child and Youth Health Paediatrics & Child Health. Jan, 2000 | Pubmed ID: 20107590 The Hippocampal Neurons of Neuronal Apoptosis Inhibitory Protein 1 (NAIP1)-deleted Mice Display Increased Vulnerability to Kainic Acid-induced Injury Proceedings of the National Academy of Sciences of the United States of America. Feb, 2000 | Pubmed ID: 10681452 High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping Ceres Kosuta1,2, Kate Daniel1, Devon L. Johnstone1,2, Kevin Mongeon1,2, Kevin Ban1,2, Sophie LeBlanc1, Stuart MacLeod1, Karim Et-Tahiry2, Marc Ekker2, Alex MacKenzie1, Izabella Pena1,2 1Children's Hospital of Eastern Ontario Research Institute, 2Department of Biology, University of Ottawa JoVE 58024 Génétique
High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping Ceres Kosuta1,2, Kate Daniel1, Devon L. Johnstone1,2, Kevin Mongeon1,2, Kevin Ban1,2, Sophie LeBlanc1, Stuart MacLeod1, Karim Et-Tahiry2, Marc Ekker2, Alex MacKenzie1, Izabella Pena1,2 1Children's Hospital of Eastern Ontario Research Institute, 2Department of Biology, University of Ottawa JoVE 58024 Génétique