Marc Ekker Department of Biology University of Ottawa Biography Publications Institution JoVE Articles Marc Ekker has not added a biography. If you are Marc Ekker and would like to personalize this page please email our Author Liaison for assistance. Publications Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency Genetics. Dec, 2017 | Pubmed ID: 29061647 Expression of Thiaminase in Zebrafish (Danio Rerio) is Lethal and Has Implications for Use As a Biocontainment Strategy in Aquaculture and Invasive Species Marine Biotechnology (New York, N.Y.). Dec, 2017 | Pubmed ID: 28980193 Lineage Tracing of Dlx1a/2a and Dlx5a/6a Expressing Cells in the Developing Zebrafish Brain Developmental Biology. 07, 2017 | Pubmed ID: 28479339 Functional Consequences of I56ii Dlx Enhancer Deletion in the Developing Mouse Forebrain Developmental Biology. Oct, 2016 | Pubmed ID: 27983964 Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus Zebrafish. 07, 2016 | Pubmed ID: 27248438 Delayed Effects of Methylmercury on the Mitochondria of Dopaminergic Neurons and Developmental Toxicity in Zebrafish Larvae (Danio Rerio) Aquatic Toxicology (Amsterdam, Netherlands). Jun, 2016 | Pubmed ID: 26994370 REMOVED: Developmental and Behavioural Abnormalities in Mice with Targeted Mutations in Dlx Enhancer Sequences International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Dec, 2015 | Pubmed ID: 29887089 Transgenic Zebrafish Expressing MCherry in the Mitochondria of Dopaminergic Neurons Zebrafish. Oct, 2015 | Pubmed ID: 26355474 Chemogenetic Ablation of Dopaminergic Neurons Leads to Transient Locomotor Impairments in Zebrafish Larvae Journal of Neurochemistry. Oct, 2015 | Pubmed ID: 26118896 Obituary of Theodore L. Sourkes, PhD, FRSC, OC Journal of Psychiatry & Neuroscience : JPN. May, 2015 | Pubmed ID: 25903035 Relative Developmental Toxicities of Pentachloroanisole and Pentachlorophenol in a Zebrafish Model (Danio Rerio) Ecotoxicology and Environmental Safety. Feb, 2015 | Pubmed ID: 25463847 The Dlx5a/dlx6a Genes Play Essential Roles in the Early Development of Zebrafish Median Fin and Pectoral Structures PloS One. 2014 | Pubmed ID: 24858471 Developmental Processes Regulated by the 3-hydroxy-3-methylglutaryl-CoA Reductase (HMGCR) Pathway: Highlights from Animal Studies Reproductive Toxicology (Elmsford, N.Y.). Jul, 2014 | Pubmed ID: 24732207 Heterogeneous Conservation of Dlx Paralog Co-expression in Jawed Vertebrates PloS One. 2013 | Pubmed ID: 23840829 The Ascl1a and Dlx Genes Have a Regulatory Role in the Development of GABAergic Interneurons in the Zebrafish Diencephalon Developmental Biology. Sep, 2013 | Pubmed ID: 23747543 The 3-hydroxy-3-methylglutaryl-CoA Reductase (HMGCR) Pathway Regulates Developmental Cerebral-vascular Stability Via Prenylation-dependent Signalling Pathway Developmental Biology. Jan, 2013 | Pubmed ID: 23206891 Functional Prediction and Physiological Characterization of a Novel Short Trans-membrane Protein 1 As a Subunit of Mitochondrial Respiratory Complexes Physiological Genomics. Dec, 2012 | Pubmed ID: 23073385 Cell Lineage Tracing Techniques for the Study of Brain Development and Regeneration International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Nov, 2012 | Pubmed ID: 22944528 The Rb/E2F Pathway Modulates Neurogenesis Through Direct Regulation of the Dlx1/Dlx2 Bigene Cluster The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2012 | Pubmed ID: 22699903 Zebrafish Parla- and Parlb-deficiency Affects Dopaminergic Neuron Patterning and Embryonic Survival Journal of Neurochemistry. Jul, 2012 | Pubmed ID: 22506991 Influences of Dietary Biotin and Avidin on Growth, Survival, Deficiency Syndrome and Hepatic Gene Expression of Juvenile Nile Tilapia Oreochromis Niloticus Fish Physiology and Biochemistry. Aug, 2012 | Pubmed ID: 22274648 Transgenic Zebrafish Expressing Green Fluorescent Protein in Dopaminergic Neurons of the Ventral Diencephalon Developmental Dynamics : an Official Publication of the American Association of Anatomists. Nov, 2011 | Pubmed ID: 21932324 Activity of Dlx5a/dlx6a Regulatory Elements During Zebrafish GABAergic Neuron Development International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Nov, 2011 | Pubmed ID: 21723936 In Vivo and in Vitro Assessment of Cardiac Beta-adrenergic Receptors in Larval Zebrafish (Danio Rerio) The Journal of Experimental Biology. May, 2011 | Pubmed ID: 21490253 Modeling Neurodegeneration in Zebrafish Current Neurology and Neuroscience Reports. Jun, 2011 | Pubmed ID: 21271309 A Key Role for Poly(ADP-ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development PloS One. 2011 | Pubmed ID: 21264220 Interactive Effects of Development and Hypoxia on Catecholamine Synthesis and Cardiac Function in Zebrafish (Danio Rerio) Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. May, 2011 | Pubmed ID: 21197535 Dysfunction in GABA Signalling Mediates Autism-like Stereotypies and Rett Syndrome Phenotypes Nature. Nov, 2010 | Pubmed ID: 21068835 Two Lamprey Hedgehog Genes Share Non-coding Regulatory Sequences and Expression Patterns with Gnathostome Hedgehogs PloS One. Oct, 2010 | Pubmed ID: 20967201 An SNP in an Ultraconserved Regulatory Element Affects Dlx5/Dlx6 Regulation in the Forebrain Development (Cambridge, England). Sep, 2010 | Pubmed ID: 20702565 The Relationship Between Dlx and Gad1 Expression Indicates Highly Conserved Genetic Pathways in the Zebrafish Forebrain Developmental Dynamics : an Official Publication of the American Association of Anatomists. Aug, 2010 | Pubmed ID: 20658694 Functional Conservation of a Forebrain Enhancer from the Elephant Shark (Callorhinchus Milii ) in Zebrafish and Mice BMC Evolutionary Biology. May, 2010 | Pubmed ID: 20504318 Impaired Dopaminergic Neuron Development and Locomotor Function in Zebrafish with Loss of Pink1 Function The European Journal of Neuroscience. Feb, 2010 | Pubmed ID: 20141529 Arcuate Nucleus Expression of NKX2.1 and DLX and Lineages Expressing These Transcription Factors in Neuropeptide Y(+), Proopiomelanocortin(+), and Tyrosine Hydroxylase(+) Neurons in Neonatal and Adult Mice The Journal of Comparative Neurology. Nov, 2009 | Pubmed ID: 19711380 Generation of Cre-transgenic Mice Using Dlx1/Dlx2 Enhancers and Their Characterization in GABAergic Interneurons Molecular and Cellular Neurosciences. Feb, 2009 | Pubmed ID: 19026749 An Endothelin-1 Switch Specifies Maxillomandibular Identity Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008 | Pubmed ID: 19017795 Functional Resolution of Duplicated Hoxb5 Genes in Teleosts Development (Cambridge, England). Nov, 2008 | Pubmed ID: 18832391 Functional Disturbances in the Striatum by Region-specific Ablation of NMDA Receptors Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008 | Pubmed ID: 18728179 Characterization of a Distinct Subpopulation of Striatal Projection Neurons Expressing the Dlx Genes in the Basal Ganglia Through the Activity of the I56ii Enhancer Developmental Biology. Oct, 2008 | Pubmed ID: 18706405 Zebrafish Dlx2a Contributes to Hindbrain Neural Crest Survival, is Necessary for Differentiation of Sensory Ganglia and Functions with Dlx1a in Maturation of the Arch Cartilage Elements Developmental Biology. Feb, 2008 | Pubmed ID: 18158147 Microarray Analysis in the Zebrafish (Danio Rerio) Liver and Telencephalon After Exposure to Low Concentration of 17alpha-ethinylestradiol Aquatic Toxicology (Amsterdam, Netherlands). Aug, 2007 | Pubmed ID: 17606305 A Subpopulation of Olfactory Bulb GABAergic Interneurons is Derived from Emx1- and Dlx5/6-expressing Progenitors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2007 | Pubmed ID: 17596436 Radiation Hybrid Maps of Medaka Chromosomes LG 12, 17, and 22 DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes. Jun, 2007 | Pubmed ID: 17591665 Molecular Dynamics of Retinoic Acid-induced Craniofacial Malformations: Implications for the Origin of Gnathostome Jaws PloS One. Jun, 2007 | Pubmed ID: 17551590 Distinct Cis-regulatory Elements from the Dlx1/Dlx2 Locus Mark Different Progenitor Cell Populations in the Ganglionic Eminences and Different Subtypes of Adult Cortical Interneurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2007 | Pubmed ID: 17494687 The Proneural Determinant MASH1 Regulates Forebrain Dlx1/2 Expression Through the I12b Intergenic Enhancer Development (Cambridge, England). May, 2007 | Pubmed ID: 17409112 The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus Neuron. Aug, 2006 | Pubmed ID: 16908411 Comparative Genomics Provides Evidence for Close Evolutionary Relationships Between the Urotensin II and Somatostatin Gene Families Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16467151 Analysis of Four DLX Homeobox Genes in Autistic Probands BMC Genetics. 2005 | Pubmed ID: 16266434 Regulatory Roles of Conserved Intergenic Domains in Vertebrate Dlx Bigene Clusters Genome Research. Apr, 2003 | Pubmed ID: 12670995 The LN54 Radiation Hybrid Map of Zebrafish Expressed Sequences Genome Research. Dec, 2001 | Pubmed ID: 11731504 Radiation Hybrid Mapping of the Zebrafish Genome Proceedings of the National Academy of Sciences of the United States of America. Aug, 1999 | Pubmed ID: 10449765 High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping Ceres Kosuta1,2, Kate Daniel1, Devon L. Johnstone1,2, Kevin Mongeon1,2, Kevin Ban1,2, Sophie LeBlanc1, Stuart MacLeod1, Karim Et-Tahiry2, Marc Ekker2, Alex MacKenzie1, Izabella Pena1,2 1Children's Hospital of Eastern Ontario Research Institute, 2Department of Biology, University of Ottawa JoVE 58024 Génétique
High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping Ceres Kosuta1,2, Kate Daniel1, Devon L. Johnstone1,2, Kevin Mongeon1,2, Kevin Ban1,2, Sophie LeBlanc1, Stuart MacLeod1, Karim Et-Tahiry2, Marc Ekker2, Alex MacKenzie1, Izabella Pena1,2 1Children's Hospital of Eastern Ontario Research Institute, 2Department of Biology, University of Ottawa JoVE 58024 Génétique