Hye Yun Kim Center for Neuro-Medicine Korea Institute of Science and Technology Biography Publications Institution JoVE Articles Hye Yun Kim has not added a biography. If you are Hye Yun Kim and would like to personalize this page please email our Author Liaison for assistance. Publications Corrigendum: EPPS Rescues Hippocampus-dependent Cognitive Deficits in APP/PS1 Mice by Disaggregation of Amyloid-β Oligomers and Plaques Nature Communications. 2016 | Pubmed ID: 26877163 Age-dependent Inverse Correlations in CSF and Plasma Amyloid-β(1-42) Concentrations Prior to Amyloid Plaque Deposition in the Brain of 3xTg-AD Mice Scientific Reports. 2016 | Pubmed ID: 26830653 EPPS Rescues Hippocampus-dependent Cognitive Deficits in APP/PS1 Mice by Disaggregation of Amyloid-β Oligomers and Plaques Nature Communications. 2015 | Pubmed ID: 26646366 Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a Cell Reports. Aug, 2015 | Pubmed ID: 26279571 Erratum To: Bis Expression in Patients with Surgically Resected Lung Cancer and Its Clinical Significance Annals of Surgical Oncology. Dec, 2015 | Pubmed ID: 26023039 Bis Expression in Patients with Surgically Resected Lung Cancer and Its Clinical Significance Annals of Surgical Oncology. Dec, 2015 | Pubmed ID: 25968616 Taurine in Drinking Water Recovers Learning and Memory in the Adult APP/PS1 Mouse Model of Alzheimer's Disease Scientific Reports. 2014 | Pubmed ID: 25502280 Correlations of Amyloid-β Concentrations Between CSF and Plasma in Acute Alzheimer Mouse Model Scientific Reports. 2014 | Pubmed ID: 25345439 Glial GABA, Synthesized by Monoamine Oxidase B, Mediates Tonic Inhibition The Journal of Physiology. Nov, 2014 | Pubmed ID: 25239459 GABA from Reactive Astrocytes Impairs Memory in Mouse Models of Alzheimer's Disease Nature Medicine. Aug, 2014 | Pubmed ID: 24973918 Discovery of Thienopyrimidine-based FLT3 Inhibitors from the Structural Modification of Known IKKβ Inhibitors Bioorganic & Medicinal Chemistry Letters. Jun, 2014 | Pubmed ID: 24813730 Aminostyrylbenzofuran Directly Reduces Oligomeric Amyloid-β and Reverses Cognitive Deficits in Alzheimer Transgenic Mice PloS One. 2014 | Pubmed ID: 24760018 Effect of Pore Sizes of PLGA Scaffolds on Mechanical Properties and Cell Behaviour for Nucleus Pulposus Regeneration in Vivo Journal of Tissue Engineering and Regenerative Medicine. Mar, 2014 | Pubmed ID: 24619952 Down-modulation of Bis Reduces the Invasive Ability of Glioma Cells Induced by TPA, Through NF-κB Mediated Activation of MMP-9 BMB Reports. May, 2014 | Pubmed ID: 24286317 2-Phenylbenzofuran Derivatives Alleviate Mitochondrial Damage Via the Inhibition of β-amyloid Aggregation Bioorganic & Medicinal Chemistry Letters. Nov, 2013 | Pubmed ID: 24076170 Effects of Red Ginseng Extract on Sleeping Behaviors in Human Volunteers Journal of Ethnopharmacology. Sep, 2013 | Pubmed ID: 23872254 Therapeutic and Pharmacokinetic Characterizations of an Anti-amyloidogenic Bis-styrylbenzene Derivative for Alzheimer's Disease Treatment Bioorganic & Medicinal Chemistry Letters. Jun, 2013 | Pubmed ID: 23601707 Amelioration of Alzheimer's Disease by Neuroprotective Effect of Sulforaphane in Animal Model Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. Mar, 2013 | Pubmed ID: 23253046 Protease Activated Receptor 1-induced Glutamate Release in Cultured Astrocytes is Mediated by Bestrophin-1 Channel but Not by Vesicular Exocytosis Molecular Brain. 2012 | Pubmed ID: 23062602 Small Molecules That Protect Against β-amyloid-induced Cytotoxicity by Inhibiting Aggregation of β-amyloid Bioorganic & Medicinal Chemistry. Aug, 2012 | Pubmed ID: 22831802 Efficient Access to Highly Pure β-amyloid Peptide by Optimized Solid-phase Synthesis Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. Sep, 2012 | Pubmed ID: 22799493 Alien Hand Syndrome After Epilepsia Partialis Continua: FDG PET and MRI Studies Epilepsy & Behavior : E&B. Jan, 2012 | Pubmed ID: 22100067 A Case of Rheumatoid Meningitis: Pathologic and Magnetic Resonance Imaging Findings Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. Dec, 2011 | Pubmed ID: 21863270 Scale-up Study of Oxalic Acid Pretreatment of Agricultural Lignocellulosic Biomass for the Production of Bioethanol Bioresource Technology. Aug, 2011 | Pubmed ID: 21632241 Response Surface Optimization of Oxalic Acid Pretreatment of Yellow Poplar (Liriodendron Tulipifera) for Production of Glucose and Xylose Monosaccarides Bioresource Technology. Jan, 2011 | Pubmed ID: 20947344 Regulation of in Vitro Aβ1-40 Aggregation Mediated by Small Molecules Journal of Alzheimer's Disease : JAD. 2010 | Pubmed ID: 20847447 Synthesis and Evaluation of Stilbene Derivatives As a Potential Imaging Agent of Amyloid Plaques Bioorganic & Medicinal Chemistry. Nov, 2010 | Pubmed ID: 20621493 Organosolv Pretreatment with Various Catalysts for Enhancing Enzymatic Hydrolysis of Pitch Pine (Pinus Rigida) Bioresource Technology. Sep, 2010 | Pubmed ID: 20435474 Magnetic Resonance Imaging of Pachymeningeal Enhancement in Vogt-Koyanagi-Harada Disease Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. Dec, 2010 | Pubmed ID: 20198496 Styryl-based Compounds As Potential in Vivo Imaging Agents for Beta-amyloid Plaques Chembiochem : a European Journal of Chemical Biology. Sep, 2007 | Pubmed ID: 17705341 Ameliorative Effects of Soy 11S Protein on Liver Damage and Hyperlipidemia in Alcohol-fed Rats Biological & Pharmaceutical Bulletin. Oct, 2004 | Pubmed ID: 15467210 Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits Hye Yun Kim1,2, Dongkeun K. Lee1, Bo-Ryehn Chung1,3, Hyunjin V. Kim1,4, YoungSoo Kim1,4 1Center for Neuro-Medicine, Korea Institute of Science and Technology, 2Research Institute, GoshenBiotech, Inc., 3Department of Chemical and Biological Engineering, Princeton University, 4Biological Chemistry Program, Korea University of Science and Technology JoVE 53308 Neurosciences
Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits Hye Yun Kim1,2, Dongkeun K. Lee1, Bo-Ryehn Chung1,3, Hyunjin V. Kim1,4, YoungSoo Kim1,4 1Center for Neuro-Medicine, Korea Institute of Science and Technology, 2Research Institute, GoshenBiotech, Inc., 3Department of Chemical and Biological Engineering, Princeton University, 4Biological Chemistry Program, Korea University of Science and Technology JoVE 53308 Neurosciences