YoungSoo Kim Center for Neuro-Medicine Korea Institute of Science and Technology Biography Publications Institution JoVE Articles YoungSoo Kim has not added a biography. If you are YoungSoo Kim and would like to personalize this page please email our Author Liaison for assistance. Publications Emodin Isolated from Polygoni Multiflori Ramulus Inhibits Melanogenesis Through the Liver X Receptor-mediated Pathway Chemico-biological Interactions. Mar, 2016 | Pubmed ID: 26972667 Corrigendum: EPPS Rescues Hippocampus-dependent Cognitive Deficits in APP/PS1 Mice by Disaggregation of Amyloid-β Oligomers and Plaques Nature Communications. 2016 | Pubmed ID: 26877163 Age-dependent Inverse Correlations in CSF and Plasma Amyloid-β(1-42) Concentrations Prior to Amyloid Plaque Deposition in the Brain of 3xTg-AD Mice Scientific Reports. 2016 | Pubmed ID: 26830653 Immunomodulatory Activities of the Benzoxathiole Derivative BOT-4-One Ameliorate Pathogenic Skin Inflammation in Mice The Journal of Investigative Dermatology. Jan, 2016 | Pubmed ID: 26763430 Targeting Long Noncoding RNA with Antisense Oligonucleotide Technology As Cancer Therapeutics Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26721493 Diterpenoids from the Roots of Euphorbia Fischeriana with Inhibitory Effects on Nitric Oxide Production Journal of Natural Products. Jan, 2016 | Pubmed ID: 26702644 Differentiation of Mammary Tumors and Reduction in Metastasis Upon Malat1 LncRNA Loss Genes & Development. Jan, 2016 | Pubmed ID: 26701265 Development of Diagnostic Biomarkers for Detecting Diabetic Retinopathy at Early Stages Using Quantitative Proteomics Journal of Diabetes Research. 2016 | Pubmed ID: 26665153 Biomarker Development for Intraductal Papillary Mucinous Neoplasms Using Multiple Reaction Monitoring Mass Spectrometry Journal of Proteome Research. Jan, 2016 | Pubmed ID: 26561977 Sesquiterpenoids from Tussilago Farfara Inhibit LPS-induced Nitric Oxide Production in Macrophage RAW 264.7 Cells Archives of Pharmacal Research. Jan, 2016 | Pubmed ID: 26474586 EPPS Rescues Hippocampus-dependent Cognitive Deficits in APP/PS1 Mice by Disaggregation of Amyloid-β Oligomers and Plaques Nature Communications. 2015 | Pubmed ID: 26646366 MicroRNA-650 in a Copy Number-variable Region Regulates the Production of Interleukin 6 in Human Osteosarcoma Cells Oncology Letters. Oct, 2015 | Pubmed ID: 26622897 AZD9150, a Next-generation Antisense Oligonucleotide Inhibitor of STAT3 with Early Evidence of Clinical Activity in Lymphoma and Lung Cancer Science Translational Medicine. Nov, 2015 | Pubmed ID: 26582900 Abnormalities of Plasma Cytokines and Spleen in Senile APP/PS1/Tau Transgenic Mouse Model Scientific Reports. 2015 | Pubmed ID: 26503550 Decreased Severity of Collagen Antibody and Lipopolysaccharide-induced Arthritis in Human IL-32β Overexpressed Transgenic Mice Oncotarget. Nov, 2015 | Pubmed ID: 26497686 Stable N-type Doping of Graphene Via High-molecular-weight Ethylene Amines Physical Chemistry Chemical Physics : PCCP. Nov, 2015 | Pubmed ID: 26496970 Age-dependent Gait Abnormalities in Mice Lacking the Rnf170 Gene Linked to Human Autosomal-dominant Sensory Ataxia Human Molecular Genetics. Dec, 2015 | Pubmed ID: 26433933 Immunomodulatory Activities of the Benzoxathiole Derivative BOT-4-One Ameliorate Pathogenic Skin Inflammation in Mice The Journal of Investigative Dermatology. Sep, 2015 | Pubmed ID: 26422381 Hypothemycin Inhibits Tumor Necrosis Factor-α Production by Tristetraprolin-dependent Down-regulation of MRNA Stability in Lipopolysaccharide-stimulated Macrophages International Immunopharmacology. Dec, 2015 | Pubmed ID: 26371861 Neo-Clerodane Diterpenoids from Scutellaria Barbata and Their Inhibitory Effects on LPS-Induced Nitric Oxide Production Journal of Natural Products. Sep, 2015 | Pubmed ID: 26331882 Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a Cell Reports. Aug, 2015 | Pubmed ID: 26279571 In-depth Characterization of the Secretome of Mouse CNS Cell Lines by LC-MS/MS Without Prefractionation Proteomics. Nov, 2015 | Pubmed ID: 26227174 Exacerbation of Collagen Antibody-induced Arthritis in Transgenic Mice Overexpressing Peroxiredoxin 6 Arthritis & Rheumatology (Hoboken, N.J.). Nov, 2015 | Pubmed ID: 26211509 Design, Synthesis, and Biological Evaluation of Benzofuran- and 2,3-dihydrobenzofuran-2-carboxylic Acid N-(substituted)phenylamide Derivatives As Anticancer Agents and Inhibitors of NF-κB Bioorganic & Medicinal Chemistry Letters. Jun, 2015 | Pubmed ID: 25953156 Geranylated Flavanones from Paulownia Coreana and Their Inhibitory Effects on Nitric Oxide Production Chemical & Pharmaceutical Bulletin. 2015 | Pubmed ID: 25948332 Adoptive Cell Therapy of Melanoma with Cytokine-induced Killer Cells Immune Network. Apr, 2015 | Pubmed ID: 25922594 Chronic Sleep Restriction Induces Long-lasting Changes in Adenosine and Noradrenaline Receptor Density in the Rat Brain Journal of Sleep Research. Oct, 2015 | Pubmed ID: 25900125 Exploration of Benzamidochromenone Derivatives with Conformational Restrictor As Interleukin-5 Inhibitors Bioorganic & Medicinal Chemistry. May, 2015 | Pubmed ID: 25865130 Saucerneol D Inhibits Dendritic Cell Activation by Inducing Heme Oxygenase-1, but Not by Directly Inhibiting Toll-like Receptor 4 Signaling Journal of Ethnopharmacology. May, 2015 | Pubmed ID: 25792017 An Ag-grid/graphene Hybrid Structure for Large-scale, Transparent, Flexible Heaters Nanoscale. Apr, 2015 | Pubmed ID: 25790123 CAMP-dependent Activation of Protein Kinase A As a Therapeutic Target of Skin Hyperpigmentation by Diphenylmethylene Hydrazinecarbothioamide British Journal of Pharmacology. Jul, 2015 | Pubmed ID: 25766244 Generation 2.5 Antisense Oligonucleotides Targeting the Androgen Receptor and Its Splice Variants Suppress Enzalutamide-resistant Prostate Cancer Cell Growth Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2015 | Pubmed ID: 25634993 Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits Hye Yun Kim1,2, Dongkeun K. Lee1, Bo-Ryehn Chung1,3, Hyunjin V. Kim1,4, YoungSoo Kim1,4 1Center for Neuro-Medicine, Korea Institute of Science and Technology, 2Research Institute, GoshenBiotech, Inc., 3Department of Chemical and Biological Engineering, Princeton University, 4Biological Chemistry Program, Korea University of Science and Technology JoVE 53308 Neurosciences
Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits Hye Yun Kim1,2, Dongkeun K. Lee1, Bo-Ryehn Chung1,3, Hyunjin V. Kim1,4, YoungSoo Kim1,4 1Center for Neuro-Medicine, Korea Institute of Science and Technology, 2Research Institute, GoshenBiotech, Inc., 3Department of Chemical and Biological Engineering, Princeton University, 4Biological Chemistry Program, Korea University of Science and Technology JoVE 53308 Neurosciences