Jaap D. van Buul Department of Molecular Cell Biology Sanquin Research and Landsteiner Laboratory, AMC at University of Amsterdam Biography Publications Institution JoVE Articles Jaap D. van Buul has not added a biography. If you are Jaap D. van Buul and would like to personalize this page please email our Author Liaison for assistance. Publications Actin-binding Proteins Differentially Regulate Endothelial Cell Stiffness, ICAM-1 Function and Neutrophil Transmigration Journal of Cell Science. Aug, 2014 | Pubmed ID: 25107367 Inhibition of GTPase Rac1 in Endothelium by 6-mercaptopurine Results in Immunosuppression in Nonimmune Cells: New Target for an Old Drug Journal of Immunology (Baltimore, Md. : 1950). May, 2014 | Pubmed ID: 24670805 Sphingosine-1-phosphate Receptor 3 Mediates Sphingosine-1-phosphate Induced Release of Weibel-palade Bodies from Endothelial Cells PloS One. 2014 | Pubmed ID: 24632890 Rho GAPs and GEFs: Controling Switches in Endothelial Cell Adhesion Cell Adhesion & Migration. Jan, 2014 | Pubmed ID: 24622613 Rho-GTPase Signaling in Leukocyte Extravasation: An Endothelial Point of View Cell Adhesion & Migration. Feb, 2014 | Pubmed ID: 24621576 P-glycoprotein Regulates Trafficking of CD8(+) T Cells to the Brain Parenchyma Acta Neuropathologica. May, 2014 | Pubmed ID: 24429546 Immunosuppressive Drug Azathioprine Reduces Aneurysm Progression Through Inhibition of Rac1 and C-Jun-terminal-N-kinase in Endothelial Cells Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2013 | Pubmed ID: 23950142 Endothelial Cell Preservation at Hypothermic to Normothermic Conditions Using Clinical and Experimental Organ Preservation Solutions Experimental Cell Research. Oct, 2013 | Pubmed ID: 23792081 The Rho-GEF Trio Regulates a Novel Pro-inflammatory Pathway Through the Transcription Factor Ets2 Biology Open. Jun, 2013 | Pubmed ID: 23789107 Endothelial Junction Regulation: a Prerequisite for Leukocytes Crossing the Vessel Wall Journal of Innate Immunity. 2013 | Pubmed ID: 23571667 Shear Stress-dependent Downregulation of the Adhesion-G Protein-coupled Receptor CD97 on Circulating Leukocytes Upon Contact with Its Ligand CD55 Journal of Immunology (Baltimore, Md. : 1950). Apr, 2013 | Pubmed ID: 23447688 The Guanine-nucleotide Exchange Factor SGEF Plays a Crucial Role in the Formation of Atherosclerosis PloS One. 2013 | Pubmed ID: 23372835 The Many Faces of the Guanine-nucleotide Exchange Factor Trio Cell Adhesion & Migration. Nov-Dec, 2012 | Pubmed ID: 23076143 The Tyrosine Phosphatase SHP2 Regulates Recovery of Endothelial Adherens Junctions Through Control of β-catenin Phosphorylation Molecular Biology of the Cell. Nov, 2012 | Pubmed ID: 22956765 Transglutaminase Activity Regulates Atherosclerotic Plaque Composition at Locations Exposed to Oscillatory Shear Stress Atherosclerosis. Oct, 2012 | Pubmed ID: 22921425 The Rho-guanine Nucleotide Exchange Factor Trio Controls Leukocyte Transendothelial Migration by Promoting Docking Structure Formation Molecular Biology of the Cell. Aug, 2012 | Pubmed ID: 22696684 The N-terminal DH-PH Domain of Trio Induces Cell Spreading and Migration by Regulating Lamellipodia Dynamics in a Rac1-dependent Fashion PloS One. 2012 | Pubmed ID: 22238672 Loss of DPP4 Activity is Related to a Prothrombogenic Status of Endothelial Cells: Implications for the Coronary Microvasculature of Myocardial Infarction Patients Basic Research in Cardiology. Jan, 2012 | Pubmed ID: 22167343 A Disintegrin and Metalloprotease 10 is a Novel Mediator of Vascular Endothelial Growth Factor-induced Endothelial Cell Function in Angiogenesis and is Associated with Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2010 | Pubmed ID: 20814017 Inside-out Regulation of ICAM-1 Dynamics in TNF-alpha-activated Endothelium PloS One. 2010 | Pubmed ID: 20596527 ICAM-1 Clustering on Endothelial Cells Recruits VCAM-1 Journal of Biomedicine & Biotechnology. 2010 | Pubmed ID: 20300427 The Regulation of Leucocyte Transendothelial Migration by Endothelial Signalling Events Cardiovascular Research. May, 2010 | Pubmed ID: 20068003 Diabetes Mellitus Induces Bone Marrow Microangiopathy Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2010 | Pubmed ID: 20042708 Cell Cycle and Tissue of Origin Contribute to the Migratory Behaviour of Human Fetal and Adult Mesenchymal Stromal Cells British Journal of Haematology. Feb, 2010 | Pubmed ID: 19863541 The Presence of Alpha-catenin in the VE-cadherin Complex is Required for Efficient Transendothelial Migration of Leukocytes International Journal of Biological Sciences. 2009 | Pubmed ID: 19918298 Endothelial Adapter Proteins in Leukocyte Transmigration Thrombosis and Haemostasis. Apr, 2009 | Pubmed ID: 19350107 Endothelial CD81 is a Marker of Early Human Atherosclerotic Plaques and Facilitates Monocyte Adhesion Cardiovascular Research. Jan, 2009 | Pubmed ID: 18805782 Filamin B Mediates ICAM-1-driven Leukocyte Transendothelial Migration The Journal of Biological Chemistry. Nov, 2008 | Pubmed ID: 18809679 RhoG Regulates Endothelial Apical Cup Assembly Downstream from ICAM1 Engagement and is Involved in Leukocyte Trans-endothelial Migration The Journal of Cell Biology. Sep, 2007 | Pubmed ID: 17875742 ICAM-1-mediated, Src- and Pyk2-dependent Vascular Endothelial Cadherin Tyrosine Phosphorylation is Required for Leukocyte Transendothelial Migration Journal of Immunology (Baltimore, Md. : 1950). Sep, 2007 | Pubmed ID: 17785844 VEGF-induced Rac1 Activation in Endothelial Cells is Regulated by the Guanine Nucleotide Exchange Factor Vav2 Experimental Cell Research. Sep, 2007 | Pubmed ID: 17686471 Endothelial Signaling by Ig-like Cell Adhesion Molecules Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2007 | Pubmed ID: 17585068 Functional Re-expression of CCR7 on CMV-specific CD8+ T Cells Upon Antigenic Stimulation International Immunology. Jun, 2005 | Pubmed ID: 15837711 Proline-rich Tyrosine Kinase 2 (Pyk2) Mediates Vascular Endothelial-cadherin-based Cell-cell Adhesion by Regulating Beta-catenin Tyrosine Phosphorylation The Journal of Biological Chemistry. Jun, 2005 | Pubmed ID: 15778498 Trading Spaces: Rap, Rac, and Rho As Architects of Transendothelial Migration Current Opinion in Hematology. Jan, 2005 | Pubmed ID: 15604886 Signaling in Leukocyte Transendothelial Migration Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2004 | Pubmed ID: 14976004 Leukocyte-endothelium Interaction Promotes SDF-1-dependent Polarization of CXCR4 The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12766157 VCAM-1-mediated Rac Signaling Controls Endothelial Cell-cell Contacts and Leukocyte Transmigration American Journal of Physiology. Cell Physiology. Aug, 2003 | Pubmed ID: 12700137 Reactive Oxygen Species Mediate Rac-induced Loss of Cell-cell Adhesion in Primary Human Endothelial Cells Journal of Cell Science. May, 2002 | Pubmed ID: 11956315 Granulocyte Colony-stimulating Factor Inhibits the Mitochondria-dependent Activation of Caspase-3 in Neutrophils Blood. Jan, 2002 | Pubmed ID: 11781253 Migration of Human Hematopoietic Progenitor Cells Across Bone Marrow Endothelium is Regulated by Vascular Endothelial Cadherin Journal of Immunology (Baltimore, Md. : 1950). Jan, 2002 | Pubmed ID: 11777950 Real-time Imaging of Endothelial Cell-cell Junctions During Neutrophil Transmigration Under Physiological Flow Jeffrey Kroon*1, Anna E. Daniel*1, Mark Hoogenboezem1, Jaap D. van Buul1 1Department of Molecular Cell Biology, Sanquin Research and Landsteiner Laboratory, AMC at University of Amsterdam JoVE 51766 Immunologie et Infection
Real-time Imaging of Endothelial Cell-cell Junctions During Neutrophil Transmigration Under Physiological Flow Jeffrey Kroon*1, Anna E. Daniel*1, Mark Hoogenboezem1, Jaap D. van Buul1 1Department of Molecular Cell Biology, Sanquin Research and Landsteiner Laboratory, AMC at University of Amsterdam JoVE 51766 Immunologie et Infection