Petra Boukamp Genetics of Skin Carcinogenesis German Cancer Research Center (DKFZ) Biography Publications Institution JoVE Articles Petra Boukamp has not added a biography. If you are Petra Boukamp and would like to personalize this page please email our Author Liaison for assistance. Publications Subcellular Raman Microspectroscopy Imaging of Nucleic Acids and Tryptophan for Distinction of Normal Human Skin Cells and Tumorigenic Keratinocytes Analytical Chemistry. Jul, 2015 | Pubmed ID: 25984831 Three-Dimensional In Vitro Skin and Skin Cancer Models Based on Human Fibroblast-Derived Matrix Tissue Engineering. Part C, Methods. May, 2015 | Pubmed ID: 25837604 Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin The Journal of Investigative Dermatology. Aug, 2015 | Pubmed ID: 25815425 Wnt-3a-activated Human Fibroblasts Promote Human Keratinocyte Proliferation and Matrix Destruction International Journal of Cancer. Journal International Du Cancer. Jun, 2015 | Pubmed ID: 25403422 Reproducibility of Telomere Length Assessment: an International Collaborative Study International Journal of Epidemiology. Sep, 2014 | Pubmed ID: 25239152 Frailty and Telomere Length: Cross-sectional Analysis in 3537 Older Adults from the ESTHER Cohort Experimental Gerontology. Oct, 2014 | Pubmed ID: 25150678 The Hallmarks of Fibroblast Ageing Mechanisms of Ageing and Development. Jun, 2014 | Pubmed ID: 24686308 The Chromatin Remodelling Complex NoRC Safeguards Genome Stability by Heterochromatin Formation at Telomeres and Centromeres EMBO Reports. Aug, 2013 | Pubmed ID: 23797874 WIF1 is Expressed by Stem Cells of the Human Interfollicular Epidermis and Acts to Suppress Keratinocyte Proliferation The Journal of Investigative Dermatology. Jun, 2013 | Pubmed ID: 23358094 An Organotypic Coculture Model Supporting Proliferation and Differentiation of Medullary Thymic Epithelial Cells and Promiscuous Gene Expression Journal of Immunology (Baltimore, Md. : 1950). Feb, 2013 | Pubmed ID: 23269248 Mechanism of the Antiproliferative Activity of Some Naphthalene Diimide G-quadruplex Ligands Molecular Pharmacology. Feb, 2013 | Pubmed ID: 23188717 Different Domains in Nidogen-1 and Nidogen-2 Drive Basement Membrane Formation in Skin Organotypic Cocultures FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2012 | Pubmed ID: 22623588 Stem Cells of the Human Epidermis and Their Niche: Composition and Function in Epidermal Regeneration and Carcinogenesis Carcinogenesis. Jul, 2012 | Pubmed ID: 22461521 UVA-induced Epigenetic Regulation of P16(INK4a) in Human Epidermal Keratinocytes and Skin Tumor Derived Cells Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Jan, 2012 | Pubmed ID: 21986889 Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O2(-):H2O2 Ratio and Confers Anoikis Resistance to Tumors Cancer Cell. Mar, 2011 | Pubmed ID: 21397862 A Decisive Function of Transforming Growth Factor-β/Smad Signaling in Tissue Morphogenesis and Differentiation of Human HaCaT Keratinocytes Molecular Biology of the Cell. Mar, 2011 | Pubmed ID: 21289094 3D Geometry-based Quantification of Colocalizations in Multichannel 3D Microscopy Images of Human Soft Tissue Tumors IEEE Transactions on Medical Imaging. Aug, 2010 | Pubmed ID: 20562043 An Inducible Tet-Off-H2B-GFP Lentiviral Reporter Vector for Detection and in Vivo Isolation of Label-retaining Cells Experimental Cell Research. Jul, 2010 | Pubmed ID: 20171964 Irradiation with Heavy-ion Particles Changes the Cellular Distribution of Human Histone Acetyltransferase HAT1 Molecular and Cellular Biochemistry. Jun, 2010 | Pubmed ID: 20148353 Ewing's Sarcoma Cells with CD57-associated Increase of Tumorigenicity and with Neural Crest-like Differentiation Capacity International Journal of Cancer. Journal International Du Cancer. Sep, 2010 | Pubmed ID: 20104521 Aging and Replicative Senescence Have Related Effects on Human Stem and Progenitor Cells PloS One. 2009 | Pubmed ID: 19513108 Tissue Context-activated Telomerase in Human Epidermis Correlates with Little Age-dependent Telomere Loss Biochimica Et Biophysica Acta. Apr, 2009 | Pubmed ID: 19419690 Dynamics of Telomeres and Promyelocytic Leukemia Nuclear Bodies in a Telomerase-negative Human Cell Line Molecular Biology of the Cell. Apr, 2009 | Pubmed ID: 19211845 Rapid Regulation of Telomere Length is Mediated by Poly(ADP-ribose) Polymerase-1 Nucleic Acids Research. Nov, 2008 | Pubmed ID: 18835851 A Stable Niche Supports Long-term Maintenance of Human Epidermal Stem Cells in Organotypic Cultures Stem Cells (Dayton, Ohio). Oct, 2008 | Pubmed ID: 18653773 Impairment of the Telomere/telomerase System and Genomic Instability Are Associated with Keratinocyte Immortalization Induced by the Skin Human Papillomavirus Type 38 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2008 | Pubmed ID: 17898088 Tumor Immune Escape by the Loss of Homeostatic Chemokine Expression Proceedings of the National Academy of Sciences of the United States of America. Nov, 2007 | Pubmed ID: 18025475 Cathepsin B is Essential for Regeneration of Scratch-wounded Normal Human Epidermal Keratinocytes European Journal of Cell Biology. Dec, 2007 | Pubmed ID: 17651862 Improved Alkaline Comet Assay Protocol for Adherent HaCaT Keratinocytes to Study UVA-induced DNA Damage Mutation Research. Jun, 2007 | Pubmed ID: 17509930 Effects of Fibroblasts and Microenvironment on Epidermal Regeneration and Tissue Function in Long-term Skin Equivalents European Journal of Cell Biology. Dec, 2007 | Pubmed ID: 17292509 The Multi-step Process of Human Skin Carcinogenesis: a Role for P53, Cyclin D1, HTERT, P16, and TSP-1 European Journal of Cell Biology. Dec, 2007 | Pubmed ID: 17198740 A Novel Regulator of Telomerase. S100A8 Mediates Differentiation-dependent and Calcium-induced Inhibition of Telomerase Activity in the Human Epidermal Keratinocyte Line HaCaT The Journal of Biological Chemistry. Mar, 2007 | Pubmed ID: 17197440 Telomeres Rather Than Telomerase a Key Target for Anti-cancer Therapy? Experimental Dermatology. Jan, 2007 | Pubmed ID: 17181645 Junctional Basement Membrane Anomalies of Skin and Mucosa in Lipoid Proteinosis (hyalinosis Cutis Et Mucosae) Journal of Dermatological Science. Mar, 2007 | Pubmed ID: 17175139 Reversion of Tumor Phenotype in Surface Transplants of Skin SCC Cells by Scaffold-induced Stroma Modulation Carcinogenesis. Mar, 2007 | Pubmed ID: 17056607 Lack of Nidogen-1 and -2 Prevents Basement Membrane Assembly in Skin-organotypic Coculture The Journal of Investigative Dermatology. Mar, 2007 | Pubmed ID: 17008882 Epidermal Homeostasis in Long-term Scaffold-enforced Skin Equivalents The Journal of Investigative Dermatology. Symposium Proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research. Sep, 2006 | Pubmed ID: 17069016 Confocal Reflection Imaging of 3D Fibrin Polymers Blood Cells, Molecules & Diseases. Mar-Apr, 2006 | Pubmed ID: 16488165 Telomere-dependent Chromosomal Instability The Journal of Investigative Dermatology. Symposium Proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research. Nov, 2005 | Pubmed ID: 16358816 Automatic Telomere Length Measurements in Interphase Nuclei by IQ-FISH Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Dec, 2005 | Pubmed ID: 16228977 C-Myc Induces Chromosomal Rearrangements Through Telomere and Chromosome Remodeling in the Interphase Nucleus Proceedings of the National Academy of Sciences of the United States of America. Jul, 2005 | Pubmed ID: 15983382 Skin Aging: a Role for Telomerase and Telomere Dynamics? Current Molecular Medicine. Mar, 2005 | Pubmed ID: 15974870 UV-induced Skin Cancer: Similarities--variations Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. Jul, 2005 | Pubmed ID: 15967008 Non-melanoma Skin Cancer: What Drives Tumor Development and Progression? Carcinogenesis. Oct, 2005 | Pubmed ID: 15905207 HaCaT Keratinocytes Secrete Lysosomal Cysteine Proteinases During Migration European Journal of Cell Biology. Dec, 2004 | Pubmed ID: 15679122 Cell Cycle-dependent 3D Distribution of Telomeres and Telomere Repeat-binding Factor 2 (TRF2) in HaCaT and HaCaT-myc Cells European Journal of Cell Biology. Dec, 2004 | Pubmed ID: 15679112 Authentic Fibroblast Matrix in Dermal Equivalents Normalises Epidermal Histogenesis and Dermoepidermal Junction in Organotypic Co-culture European Journal of Cell Biology. Dec, 2004 | Pubmed ID: 15679108 The Three-dimensional Organization of Telomeres in the Nucleus of Mammalian Cells BMC Biology. 2004 | Pubmed ID: 15176976 Constitutive Overexpression of Human Telomerase Reverse Transcriptase but Not C-myc Blocks Terminal Differentiation in Human HaCaT Skin Keratinocytes The Journal of Investigative Dermatology. Jul, 2003 | Pubmed ID: 12839571 The E6 and E7 Proteins of the Cutaneous Human Papillomavirus Type 38 Display Transforming Properties Journal of Virology. Feb, 2003 | Pubmed ID: 12525654 UV-B-type Mutations and Chromosomal Imbalances Indicate Common Pathways for the Development of Merkel and Skin Squamous Cell Carcinomas International Journal of Cancer. Journal International Du Cancer. May, 2002 | Pubmed ID: 11992403 Human Dermal Fibroblasts Escape from the Long-term Phenocopy of Senescence Induced by Psoralen Photoactivation Experimental Cell Research. Apr, 2002 | Pubmed ID: 11900490 Dual Regulation of Telomerase Activity Through C-Myc-dependent Inhibition and Alternative Splicing of HTERT Journal of Cell Science. Mar, 2002 | Pubmed ID: 11884529 3D Organotypic Co-culture Model Supporting Medullary Thymic Epithelial Cell Proliferation, Differentiation and Promiscuous Gene Expression Sheena Pinto*1, Hans-Jürgen Stark*2, Iris Martin2, Petra Boukamp2, Bruno Kyewski1 1Division of Developmental Immunology, German Cancer Research Center (DKFZ), 2Genetics of Skin Carcinogenesis, German Cancer Research Center (DKFZ) JoVE 52614 Biologie du développement
3D Organotypic Co-culture Model Supporting Medullary Thymic Epithelial Cell Proliferation, Differentiation and Promiscuous Gene Expression Sheena Pinto*1, Hans-Jürgen Stark*2, Iris Martin2, Petra Boukamp2, Bruno Kyewski1 1Division of Developmental Immunology, German Cancer Research Center (DKFZ), 2Genetics of Skin Carcinogenesis, German Cancer Research Center (DKFZ) JoVE 52614 Biologie du développement