Yoshihiro Urade International Institute for Integrative Sleep Medicine (WPI-IIIS) University of Tsukuba Biography Publications Institution JoVE Articles Yoshihiro Urade has not added a biography. If you are Yoshihiro Urade and would like to personalize this page please email our Author Liaison for assistance. Publications Japanese Sake Yeast Supplementation Improves the Quality of Sleep: a Double-blind Randomised Controlled Clinical Trial Journal of Sleep Research. Sep, 2015 | Pubmed ID: 26354605 PGD2 Deficiency Exacerbates Food Antigen-induced Mast Cell Hyperplasia Nature Communications. 2015 | Pubmed ID: 26159556 Zinc-containing Yeast Extract Promotes Nonrapid Eye Movement Sleep in Mice Molecular Nutrition & Food Research. Oct, 2015 | Pubmed ID: 26105624 The Roles of Prostaglandin E2 and D2 in Lipopolysaccharide-mediated Changes in Sleep Brain, Behavior, and Immunity. Jul, 2015 | Pubmed ID: 25532785 Doxepin and Diphenhydramine Increased Non-rapid Eye Movement Sleep Through Blockade of Histamine H1 Receptors Pharmacology, Biochemistry, and Behavior. Feb, 2015 | Pubmed ID: 25498564 Prostaglandin D2 Synthase/GPR44: a Signaling Axis in PNS Myelination Nature Neuroscience. Dec, 2014 | Pubmed ID: 25362470 Acid Reflux Directly Causes Sleep Disturbances in Rat with Chronic Esophagitis PloS One. 2014 | Pubmed ID: 25215524 Prostaglandin D2 Acts Through the Dp2 Receptor to Influence Male Germ Cell Differentiation in the Foetal Mouse Testis Development (Cambridge, England). Sep, 2014 | Pubmed ID: 25142465 Lipocalin-type Prostaglandin D Synthase Scavenges Biliverdin in the Cerebrospinal Fluid of Patients with Aneurysmal Subarachnoid Hemorrhage Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2014 | Pubmed ID: 25005874 Transcriptional Regulation in Adipogenesis Through PPARγ-dependent and -independent Mechanisms by Prostaglandins Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24927844 Mast Cell-derived Prostaglandin D2 Inhibits Colitis and Colitis-associated Colon Cancer in Mice Cancer Research. Jun, 2014 | Pubmed ID: 24879565 Characterization of Four New Designer Drugs, 5-chloro-NNEI, NNEI Indazole Analog, α-PHPP and α-POP, with 11 Newly Distributed Designer Drugs in Illegal Products Forensic Science International. Oct, 2014 | Pubmed ID: 24769262 Association of Lipocalin-type Prostaglandin D Synthase with Disproportionately Enlarged Subarachnoid-space in Idiopathic Normal Pressure Hydrocephalus Fluids and Barriers of the CNS. 2014 | Pubmed ID: 24731502 Intestinal Tumor Suppression in ApcMin/+ Mice by Prostaglandin D2 Receptor PTGDR Cancer Medicine. Aug, 2014 | Pubmed ID: 24729479 Piromelatine Exerts Antinociceptive Effect Via Melatonin, Opioid, and 5HT1A Receptors and Hypnotic Effect Via Melatonin Receptors in a Mouse Model of Neuropathic Pain Psychopharmacology. Oct, 2014 | Pubmed ID: 24700387 Immunosuppression Via Adenosine Receptor Activation by Adenosine Monophosphate Released from Apoptotic Cells ELife. 2014 | Pubmed ID: 24668173 Practical Evaluation of Liquid Chromatography/tandem Mass Spectrometry and Enzyme Immunoassay Method for the Accurate Quantitative Analysis of Prostaglandins Journal of Bioscience and Bioengineering. Jul, 2014 | Pubmed ID: 24534197 Marine Polyphenol Phlorotannins Promote Non-rapid Eye Movement Sleep in Mice Via the Benzodiazepine Site of the GABAA Receptor Psychopharmacology. Jul, 2014 | Pubmed ID: 24488362 δ-Opioid Receptor Activation Stimulates Normal Diet Intake but Conversely Suppresses High-fat Diet Intake in Mice American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Feb, 2014 | Pubmed ID: 24401991 Prostaglandin D(2) is Crucial for Seizure Suppression and Postictal Sleep Experimental Neurology. Mar, 2014 | Pubmed ID: 24333565 A Mouse Model Mimicking Human First Night Effect for the Evaluation of Hypnotics Pharmacology, Biochemistry, and Behavior. Jan, 2014 | Pubmed ID: 24316349 Opposing Immunomodulatory Roles of Prostaglandin D2 During the Progression of Skin Inflammation Journal of Immunology (Baltimore, Md. : 1950). Jan, 2014 | Pubmed ID: 24298012 Endogenous Prostaglandin D2 and Its Metabolites Protect the Heart Against Ischemia-reperfusion Injury by Activating Nrf2 Hypertension. Jan, 2014 | Pubmed ID: 24101662 GABA Transporter-1 Inhibitor NO-711 Alters the EEG Power Spectra and Enhances Non-rapid Eye Movement Sleep During the Active Phase in Mice European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. Apr, 2014 | Pubmed ID: 24080505 Bofutsushosan, a Japanese Herbal (Kampo) Medicine, Attenuates Progression of Nonalcoholic Steatohepatitis in Mice Journal of Gastroenterology. Jun, 2014 | Pubmed ID: 23800945 Projections of Nucleus Accumbens Adenosine A2A Receptor Neurons in the Mouse Brain and Their Implications in Mediating Sleep-wake Regulation Frontiers in Neuroanatomy. 2013 | Pubmed ID: 24409122 Essential Roles of GABA Transporter-1 in Controlling Rapid Eye Movement Sleep and in Increased Slow Wave Activity After Sleep Deprivation PloS One. 2013 | Pubmed ID: 24155871 New Insights into the Catalytic Mechanism of Bombyx Mori Prostaglandin E Synthase Gained from Structure-function Analysis Biochemical and Biophysical Research Communications. Nov, 2013 | Pubmed ID: 24120949 Roles of Adrenergic α1 and Dopamine D1 and D2 Receptors in the Mediation of the Desynchronization Effects of Modafinil in a Mouse EEG Synchronization Model PloS One. 2013 | Pubmed ID: 24116090 Elevated CSF Histamine Levels in Multiple Sclerosis Patients Fluids and Barriers of the CNS. 2013 | Pubmed ID: 23659456 Mast Cell Maturation is Driven Via a Group III Phospholipase A2-prostaglandin D2-DP1 Receptor Paracrine Axis Nature Immunology. Jun, 2013 | Pubmed ID: 23624557 FASTER: an Unsupervised Fully Automated Sleep Staging Method for Mice Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Jun, 2013 | Pubmed ID: 23621645 A Prostaglandin D2 Metabolite is Elevated in the Urine of Duchenne Muscular Dystrophy Patients and Increases Further from 8 Years Old Clinica Chimica Acta; International Journal of Clinical Chemistry. Aug, 2013 | Pubmed ID: 23603101 Anti-inflammatory Role of PGD2 in Acute Lung Inflammation and Therapeutic Application of Its Signal Enhancement Proceedings of the National Academy of Sciences of the United States of America. Mar, 2013 | Pubmed ID: 23479612 Role of the Basal Ganglia in the Control of Sleep and Wakefulness Current Opinion in Neurobiology. Oct, 2013 | Pubmed ID: 23465424 Crystal Structure of a Bombyx Mori Sigma-class Glutathione Transferase Exhibiting Prostaglandin E Synthase Activity Biochimica Et Biophysica Acta. Jun, 2013 | Pubmed ID: 23458683 Mast Cells Contribute to Double-stranded RNA-induced Augmentation of Airway Eosinophilia in a Murine Model of Asthma Respiratory Research. 2013 | Pubmed ID: 23452625 Morphine Inhibits Sleep-promoting Neurons in the Ventrolateral Preoptic Area Via Mu Receptors and Induces Wakefulness in Rats Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Apr, 2013 | Pubmed ID: 23303062 Drug Transporters on Arachnoid Barrier Cells Contribute to the Blood-cerebrospinal Fluid Barrier Drug Metabolism and Disposition: the Biological Fate of Chemicals. Apr, 2013 | Pubmed ID: 23298861 A Urine Biomarker for Severe Obstructive Sleep Apnoea Patients: Lipocalin-type Prostaglandin D Synthase The European Respiratory Journal. Dec, 2013 | Pubmed ID: 23222881 The Lipocalin-type Prostaglandin D2 Synthase Knockout Mouse Model of Insulin Resistance and Obesity Demonstrates Early Hypothalamic-pituitary-adrenal Axis Hyperactivity The Journal of Endocrinology. Feb, 2013 | Pubmed ID: 23151358 Unilateral Cryptorchidism in Mice Mutant for Ptgds Human Mutation. Feb, 2013 | Pubmed ID: 23076868 The Role of Nucleus Accumbens Core/shell in Sleep-wake Regulation and Their Involvement in Modafinil-induced Arousal PloS One. 2012 | Pubmed ID: 23029032 Dopamine is Involved in Food-anticipatory Activity in Mice Journal of Biological Rhythms. Oct, 2012 | Pubmed ID: 23010662 PGD2-CRTH2 Pathway Promotes Tubulointerstitial Fibrosis Journal of the American Society of Nephrology : JASN. Nov, 2012 | Pubmed ID: 22997255 Proteomic Analysis of Cerebrospinal Fluid Before and After Intrathecal Injection of Steroid into Patients with Postherpetic Pain Proteomics. Oct, 2012 | Pubmed ID: 22936653 A New Role for Lipocalin Prostaglandin D Synthase in the Regulation of Brown Adipose Tissue Substrate Utilization Diabetes. Dec, 2012 | Pubmed ID: 22923471 How Do the Basal Ganglia Regulate Sleep-wake Behavior? Trends in Neurosciences. Dec, 2012 | Pubmed ID: 22858523 [Endogenous Sleep-promoting Substance] Nihon Rinsho. Japanese Journal of Clinical Medicine. Jul, 2012 | Pubmed ID: 22844810 Lipocalin Prostaglandin D Synthase and PPARγ2 Coordinate to Regulate Carbohydrate and Lipid Metabolism in Vivo PloS One. 2012 | Pubmed ID: 22792179 Magnolol, a Major Bioactive Constituent of the Bark of Magnolia Officinalis, Induces Sleep Via the Benzodiazepine Site of GABA(A) Receptor in Mice Neuropharmacology. Nov, 2012 | Pubmed ID: 22771461 Orally Administered Rubiscolin-6, a δ Opioid Peptide Derived from Rubisco, Stimulates Food Intake Via Leptomeningeal Lipocallin-type Prostaglandin D Synthase in Mice Molecular Nutrition & Food Research. Aug, 2012 | Pubmed ID: 22715053 Activation of Adipogenesis by Lipocalin-type Prostaglandin D Synthase-generated Δ¹²-PGJ₂ Acting Through PPARγ-dependent and Independent Pathways Gene. Aug, 2012 | Pubmed ID: 22664386 Polygraphic Recording Procedure for Measuring Sleep in Mice Yo Oishi1, Yohko Takata1, Yujiro Taguchi2, Sayaka Kohtoh2, Yoshihiro Urade1, Michael Lazarus1 1International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 2Public Sector/Medical Solutions, Kissei Comtech Co., Ltd JoVE 53678 Neurosciences
Polygraphic Recording Procedure for Measuring Sleep in Mice Yo Oishi1, Yohko Takata1, Yujiro Taguchi2, Sayaka Kohtoh2, Yoshihiro Urade1, Michael Lazarus1 1International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 2Public Sector/Medical Solutions, Kissei Comtech Co., Ltd JoVE 53678 Neurosciences