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Midline Laparotomy Surgery in Recipient Mice for Orthotopic Liver Transplantation (Video) | JoVE

Midline Laparotomy Surgery in Recipient Mice for Orthotopic Liver Transplantation (Video) | JoVE

Liver Transplantation in Mouse and Analyzing Allograft Patency

Article DOI: 10.3791/200622-v • 02:33 min • September 22nd, 2023

September 22nd, 2023 •

Qiang Zeng¹, Doug A. Gouchoe^2,3, Mahboubeh Nabavinia⁴, Yong Gyu Lee², Xi Wang², Terri A. Shaffer⁵, Mitchel R. Stacy^4,5,6, Blake R. Peterson^7,8, Bryan A. Whitson^2,9, Christopher Breuer^1,4, Sylvester M. Black^1,10

¹Department of Surgery, Nationwide Children’s Hospital, ²COPPER Laboratory, The Ohio State University, ³88th Surgical Operation Operations Squadron, WPAFB, ⁴Center for Regenerative Medicine, The Research Institute at Nationwide Children’s Hospital, ⁵Division of Vascular Diseases and Surgery, The Ohio State University College of Medicine, ⁶Interdisciplinary Biophysics Graduate Program, The Ohio State University, ⁷Division of Medicinal Chemistry and Pharmacognosy, The Ohio State University College of Pharmacy, ⁸The Ohio State University Comprehensive Cancer Center, ⁹Division of Cardiac Surgery, Department of Surgery, The Ohio State Wexner Medical Center, ¹⁰Division of Transplantation, Department of Surgery, The Ohio State Wexner Medical Center

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Keywords: Orthotopic Liver Transplantation Microcomputed Tomography Angiography Mouse Model Allograft Injury Vascular Anastomosis Thrombosis Contrast Timing Cardiac Gating Isoflurane Longitudinal Evaluation Transplantation Research

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