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Analytical Techniques for Assaying Nitric Oxide Bioactivity
 

Analytical Techniques for Assaying Nitric Oxide Bioactivity

Article DOI: 10.3791/3722-v • 11:28 min • June 18th, 2012
June 18th, 2012 •
1, 1, 1, 2, 1
1Texas Therapeutics Institute, University of Texas Health Science Center at Houston, 2Deptartment of Pediatrics, Baylor College of Medicine

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résumé
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The endogenous production of nitric oxide (NO) regulates a wide variety of biological functions. It is becoming increasingly clear that disruption or dysregulation of NO based signaling is involved in many human diseases. Methods to quantify relevant NO metabolites may provide novel diagnostic or prognostic biomarkers for human disease.

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Analytical Techniques Assaying Nitric Oxide Bioactivity Detection Quantification Signaling Molecules Blood Pressure Regulation Immune Response Regulation Neural Communication Regulation Accurate Detection Quantification In Biological Matrices Physiological Half Life Alternative Strategies Detection Of Reaction Products NO Metabolites Biological Compartments In Vivo NO Production Bioavailability Metabolism Whole Body NO Status Tissues Diagnostic Utility Prognostic Utility NO Biomarkers
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