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Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease
 

Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease

Article DOI: 10.3791/50303-v 10:32 min June 17th, 2013
June 17th, 2013

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résumé

In Parkinson's disease and movement disorders in general, sensitive and reliable behavioral assays are essential for testing novel potential therapeutics. Here, we describe a manageable battery of sensorimotor tests for mice that are sensitive to varying degrees of injury to the nigrostriatal system and useful for preclinical studies.

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Keywords: Sensorimotor Function Mouse Models Parkinson's Disease Behavioral Outcome Measures Preclinical Trials Nigrostriatal Dysfunction Sensorimotor Tests Genetic Mouse Models Disease-modifying Therapies
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