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Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
 

Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography

Article DOI: 10.3791/51041-v • 10:33 min • February 3rd, 2014
February 3rd, 2014 •
*1,2, *1, 1, 1, 1, 1, 1, 1, 1, 1
1Cardiac Muscle Research Labratory, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, 2Cardiovascular Department, Chang Gung Memorial Hospital
* These authors contributed equally

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résumé
Automatic Translation

Right ventricle (RV) dysfunction is critical to the pathogenesis of cardiovascular disease, yet limited methodologies are available for its evaluation. Recent advances in ultrasound imaging provide a noninvasive and accurate option for longitudinal RV study. Herein, we detail a step-by-step echocardiographic method using a murine model of RV pressure overload.

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Keywords: Right Ventricular Structure Right Ventricular Function Pulmonary Artery Constriction Transthoracic Echocardiography Mouse Model Cardiac Pathology Pressure Gradient Ventricular Dysfunction Pulmonary Artery Hypertension Noninvasive Assessment Echocardiographic Measurements
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